THE INFLUENCE OF SOMATOSTATIN ON CALCITONIN SECRETION IN ALBINO-RATS

被引:0
作者
GOZARIUSTRIMBU, M
SANDOR, V
ORBAI, P
CUPARENCU, B
GOZARIU, L
STRIMBU, C
LOSASSO, C
LOFFREDA, A
LAMPA, E
机构
[1] UNIV NAPLES,FAC MED & SURG 1,INST PHARMACOL & TOXICOL,I-80138 NAPLES,ITALY
[2] MED & PHARMACEUT INST,DEPT PHARMACOL & ENDOCRINOL,CLUJ NAPOCA,ROMANIA
来源
CURRENT THERAPEUTIC RESEARCH-CLINICAL AND EXPERIMENTAL | 1994年 / 55卷 / 08期
关键词
D O I
10.1016/S0011-393X(05)80589-2
中图分类号
R-3 [医学研究方法]; R3 [基础医学];
学科分类号
1001 ;
摘要
The effects of somatostatin on calcitonin secretion were studied in male Wistar albino rats. In anesthetized rats, the administration of synthetic somatostatin induced a reduction in the calcitonin content of the thyroid. In animals with destroyed central adrenergic neurons, the effects of somatostatin were less visible. An intravenous injection of somatostatin did not affect the baseline calcitonin level, but it did prevent the rise in calcitonin concentration elicited by the intravenous administration of calcium gluconate.
引用
收藏
页码:971 / 975
页数:5
相关论文
共 12 条
  • [1] BROZEAU P, 1973, SCIENCE, V179, P77
  • [2] CARE AD, 1978, ENDOCRINOLOGY, V102, P745
  • [3] De Groot J., 1959, RAT FOREBRAIN STEREO
  • [5] GOZARIU L, 1988, 8TH INT C END KYOT, P532
  • [6] GOZARIU M, 1989, CURR THER RES CLIN E, V45, P116
  • [7] EFFECT OF SOMATOSTATIN ON PARATHYROID-HORMONE AND CALCITONIN SECRETION
    HARGIS, GK
    WILLIAMS, GA
    REYNOLDS, WA
    CHERTOW, BS
    KUKREJA, SC
    BOWSER, EN
    HENDERSON, WJ
    [J]. ENDOCRINOLOGY, 1978, 102 (03) : 745 - 750
  • [8] THYROCALCITONIN
    HIRSCH, PF
    MUNSON, PL
    [J]. PHYSIOLOGICAL REVIEWS, 1969, 49 (03) : 548 - +
  • [9] NEUROENDOCRINE MODULATION OF CALCITONIN AND PARATHYROID-HORMONE IN MAN
    METZ, SA
    DEFTOS, LJ
    BAYLINK, DJ
    ROBERTSON, RP
    [J]. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 1978, 47 (01) : 151 - 159
  • [10] MULLER OA, 1977, ACTA ENDOCR-COP S208, V84, P46