SELF-ORGANIZATION OF POLYMER-MOTOR SYSTEMS IN THE CYTOSKELETON

被引：48
作者：
MITCHISON, TJ
机构：
[1] Department of Pharmacology, University of California, Francisco
来源：
PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY OF LONDON SERIES B-BIOLOGICAL SCIENCES | 1992年 / 336卷 / 1276期
关键词：
D O I：
10.1098/rstb.1992.0049
中图分类号：
Q [生物科学];
学科分类号：
07 ; 0710 ; 09 ;
摘要：
Microtubules and actin filaments are organized into dynamic arrays inside cells. In this paper I discuss in conceptual form the assembly mechanisms of three specific arrays: asters, spindles and leading edge structures. The role of energy transducing processes, particularly motor protein activity, in assembly is explored. I conclude that dynamic interaction between motor proteins and cytoskeletal polymers play a very general role in spatial organization of the cytoplasm.
引用
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页码：99 / 106
页数：8
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