MAPPING OF THE THROMBOSPONDIN GENE TO HUMAN CHROMOSOME-15 AND MOUSE CHROMOSOME-2 BY INSITU HYBRIDIZATION

被引：34

作者：

JAFFE, E

BORNSTEIN, P

DISTECHE, CM

机构：

[1] UNIV WASHINGTON,DEPT PATHOL,SEATTLE,WA 98195

[2] UNIV WASHINGTON,DEPT BIOCHEM,SEATTLE,WA 98195

[3] UNIV WASHINGTON,DEPT MED,SEATTLE,WA 98195

来源：

GENOMICS | 1990年 / 7卷 / 01期

关键词：

D O I：

10.1016/0888-7543(90)90528-3

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

We have mapped the thrombospondin gene (THBS1) to a single locus on human chromosome 15 (band q15) and on mouse chromosome 2 (region F). Thrombospondin has been implicated in a variety of cell-matrix and cell-cell interactions. The finding of a single locus suggests that the different functions of thrombospondin are not due to a closely related family of genes. These results also confirm a region of homology between the proximal part of human chromosome 15 and region F of mouse chromosome 2. © 1990.

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页码：123 / 126

页数：4

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