STRUCTURE AND CONFORMATION OF 3'-AZIDO-3'-DEOXYTHYMIDINE (AZT), AN INHIBITOR OF THE HIV (AIDS) VIRUS

被引：79
作者：
BIRNBAUM, GI
GIZIEWICZ, J
GABE, EJ
LIN, TS
PRUSOFF, WH
机构：
[1] NATL RES COUNCIL CANADA,DIV CHEM,OTTAWA K1A 0R6,ONTARIO,CANADA
[2] YALE UNIV,SCH MED,DEPT PHARMACOL,NEW HAVEN,CT 06510
来源：
CANADIAN JOURNAL OF CHEMISTRY-REVUE CANADIENNE DE CHIMIE | 1987年 / 65卷 / 09期
关键词：
D O I：
10.1139/v87-356
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
引用
收藏
页码：2135 / 2139
页数：5
相关论文
共 22 条
[1]   SYSTEMATIC ANALYSIS OF STRUCTURAL DATA AS A RESEARCH TECHNIQUE IN ORGANIC-CHEMISTRY [J].
ALLEN, FH ;
KENNARD, O ;
TAYLOR, R .
ACCOUNTS OF CHEMICAL RESEARCH, 1983, 16 (05) :146-153
[2]   CARCINOGENIC ALKYLATION OF NUCLEIC-ACID BASES - STRUCTURE AND CONFORMATION OF O4-ETHYL-2'-DEOXYTHYMIDINE IN THE SOLID-STATE AND IN SOLUTION [J].
BIRNBAUM, GI ;
SADANA, KL ;
BLONSKI, WJP ;
HRUSKA, FE .
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1986, 108 (07) :1671-1675
[3]   STRUCTURE AND CONFORMATION OF THE ANTICODON NUCLEOSIDE 5-METHOXYURIDINE IN THE SOLID-STATE AND IN SOLUTION [J].
BIRNBAUM, GI ;
BLONSKI, WJP ;
HRUSKA, FE .
CANADIAN JOURNAL OF CHEMISTRY-REVUE CANADIENNE DE CHIMIE, 1983, 61 (10) :2299-2304
[4]   NOVEL ZWITTERIONIC STRUCTURE AND AN UNUSUAL SUGAR RING CONFORMATION IN 5-IODO-5'-AMINO-2',5'-DIDEOXYURIDINE, AN ANTI-VIRAL NUCLEOSIDE [J].
BIRNBAUM, GI ;
LIN, TS ;
SHIAU, GT ;
PRUSOFF, WH .
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1979, 101 (12) :3353-3358
[5]  
BIRNBAUM GI, IN PRESS TOPICS NU 3
[6]  
DELEEUW HPM, 1980, ISRAEL J CHEM, V20, P108
[7]   INDUCTION OF ENDOGENOUS AND OF SPLEEN FOCUS-FORMING VIRUSES DURING DIMETHYLSULFOXIDE-INDUCED DIFFERENTIATION OF MOUSE ERYTHROLEUKEMIA CELLS TRANSFORMED BY SPLEEN FOCUS-FORMING VIRUS [J].
DUBE, SK ;
PRAGNELL, IB ;
KLUGE, N ;
GAEDICKE, G ;
STEINHEIDER, G ;
OSTERTAG, W .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1975, 72 (05) :1863-1867
[8]  
Gabe E. J., 1985, CRYSTALLOGRAPHIC COM, V3, P167
[9]   5-IODO-2'-DEOXYCYTIDINE [J].
GHIASSY, F ;
LOW, JN ;
WILSON, HR .
ACTA CRYSTALLOGRAPHICA SECTION B-STRUCTURAL SCIENCE, 1981, 37 (OCT) :1921-1923
[10]   ANALYSIS OF SINGLE-CRYSTAL BRAGG-REFLECTIONS FROM PROFILE MEASUREMENTS [J].
GRANT, DF ;
GABE, EJ .
JOURNAL OF APPLIED CRYSTALLOGRAPHY, 1978, 11 (APR) :114-120
123