ABNORMAL PHOSPHORYLATION OF THE MICROTUBULE-ASSOCIATED PROTEIN-TAU (TAU) IN ALZHEIMER CYTOSKELETAL PATHOLOGY

被引：3109

作者：

GRUNDKEIQBAL, I ^{[1
]}

IQBAL, K ^{[1
]}

TUNG, YC ^{[1
]}

QUINLAN, M ^{[1
]}

WISNIEWSKI, HM ^{[1
]}

BINDER, LI ^{[1
]}

机构：

[1] UNIV ALABAMA,DEPT CELL BIOL & ANAT,BIRMINGHAM,AL 35294

来源：

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA | 1986年 / 83卷 / 13期

关键词：

D O I：

10.1073/pnas.83.13.4913

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

引用

页码：4913 / 4917

页数：5

共 21 条

[1]

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[2]

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[3]

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[4] ALZHEIMER PAIRED HELICAL FILAMENTS - IDENTIFICATION OF POLYPEPTIDES WITH MONOCLONAL-ANTIBODIES [J].

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IQBAL, K ;

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[5] ALZHEIMER PAIRED HELICAL FILAMENTS - IMMUNOCHEMICAL IDENTIFICATION OF POLYPEPTIDES [J].

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IQBAL, K ;

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[6]

GRUNDKEIQBAL I, 1986, J BIOL CHEM, V261, P6084

[7] ALZHEIMER PAIRED HELICAL FILAMENTS - CROSS-REACTING POLYPEPTIDE/S NORMALLY PRESENT IN BRAIN [J].

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IQBAL, K ;

TUNG, YC ;

WANG, GP ;

WISNIEWSKI, HM .

ACTA NEUROPATHOLOGICA, 1985, 66 (01) :52-61

[8] ALZHEIMER PAIRED HELICAL FILAMENTS - BULK ISOLATION, SOLUBILITY, AND PROTEIN-COMPOSITION [J].

IQBAL, K ;

ZAIDI, T ;

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MERZ, PA ;

WISNIEWSKI, HM .

ACTA NEUROPATHOLOGICA, 1984, 62 (03) :167-177

[9] INVITRO ASSEMBLY OF MICROTUBULES AND NEUROFILAMENTS FROM ALZHEIMER BRAIN [J].

IQBAL, K ;

MERZ, PA ;

WISNIEWSKI, HM .

JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY, 1982, 41 (03) :364-364

[10] CLEAVAGE OF STRUCTURAL PROTEINS DURING ASSEMBLY OF HEAD OF BACTERIOPHAGE-T4 [J].

LAEMMLI, UK .

NATURE, 1970, 227 (5259) :680-+

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