THE PB3300 INTRAARTERIAL BLOOD-GAS MONITORING-SYSTEM

Continuous intraarterial blood gas (IABG) monitoring is in clinical use both in the operating room and intensive care unit. This technology uses miniature, optically-based sensors that can be placed into a patient's artery. The arterial blood gas values are transduced into an optical signal that is measured by a bedside monitor on which the values are displayed. In this paper, we describe the operating principles of the PB3300 Intra-Arterial Blood Gas Monitoring System (Puritan-Bennett Corporation, FOxS Division, Carlsbad, CA). Topics include the principles of fluorescent determinations of pH, PCO2, and PO2; the optical path of the PB3300; system calibration; dye layer geometry; and clinical operation. The accuracy, precision, and drift of the system measuring tonometered aqueous standards are reported. The following values were noted for eight sensors sending data to eight monitors: system bias and precisions of 0.00 +/- 0.02 pH at a pH of 7.40, -2.5 +/- 1.5 mm Hg PCO2 at a PCO2 of 40 mm Hg, and 3.3 +/- 1.3 mm Hg PO2 at a PO2 of 80 mm Hg.