RAPIDLY PROGRESSIVE PULMONARY ALVEOLAR PROTEINOSIS IN A PATIENT WITH CHRONIC MYELOGENOUS LEUKEMIA

被引:13
作者
ITO, K [1 ]
IWABE, K [1 ]
OKAI, T [1 ]
KOUDA, S [1 ]
TADOKORO, M [1 ]
ISIKO, T [1 ]
机构
[1] KAWAKITA GEN HOSP,DEPT INTERNAL MED,1-7-3 ASAGAYA KITA,SUGINAMI KU,TOKYO 166,JAPAN
关键词
INTERFERON-ALPHA; CELL-MEDIATED IMMUNITY; PULMONARY ALVEOLAR PHOSPHOLIPOPROTEINOSIS;
D O I
10.2169/internalmedicine.33.710
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
A 46-year-old man with chronic myelogenous leukemia (CML) was admitted to our hospital because of high fever. The chest radiographs showed bilateral groundglass-like infiltrates in the perihilar region. Transbronchial lung biopsy (TBLB) and autopsy revealed PAS-positive granular materials characteristic of pulmonary aleveolar proteinosis (PAP). He had received interferon-alpha since the time of CML diagnosis. Busulfan had never been administered. Altered cell-mediated immunity was thought to be closely related to the development of PAP.
引用
收藏
页码:710 / 713
页数:4
相关论文
共 12 条
  • [1] Bedrossian C.W.M., Luna M.A., Conklin R.H., Alveolar proteinosis as a consequence of immunosuppression, Hum Pathol, 11, (1980)
  • [2] Green D., Dighe P., Ali N.O., Pulmonary alveolar proteinosis complicating chronic myelogenous leukemia, Cancer, 46, (1980)
  • [3] Israel R.H., Magnussen C.R., Are AIDS patients at risk for pulmonary alveolar proteinosis?, Chest, 96, (1989)
  • [4] Prakash U.B.S., Barham S.S., Carpenter H.A., Pulmonary alveolar phospholipoproteinosis: experience with 34 cases and a review, Mayo Clin Proc, 62, (1987)
  • [5] Rosen S.H., Castleman B., Liebow A.A., New Engl J Med, 258, (1958)
  • [6] Smith F.B., Alveolar proteinosis: atypical pulmonary response to injury, NY State J Med, 80, (1980)
  • [7] Watanabe K., Sueishi K., Tanaka K., Pulmonary alveolar proteinosis and disseminated atypical mycobacteriosis in a patient with busulfan lung, Acta Pathol Jpn, 40, (1990)
  • [8] Wilson J.F., Busulfan-associated bronchopulmonary dysplasia in two patients with chronic myelogenous leukemia, Am J Clin Pathol, 50, (1968)
  • [9] Colon A.R., Lawrence R.D., Mills S.D., Childhood pulmonary alveolar proteinosis, Report of a case and review of the literature. Am J Dis Child, 121, (1971)
  • [10] Yamaryo T., Nagai H., Kurashima A., Two cases of interstitial pneumonia induced by interferon-alpha, The Japanese J Chest Diseases, 52, (1993)