AUDITORY NEURONS WITH TRANSITORY AXONS TO VISUAL AREAS FORM SHORT PERMANENT PROJECTIONS

被引:10
作者
CLARKE, S [1 ]
INNOCENTI, GM [1 ]
机构
[1] UNIV LAUSANNE,INST ANAT,CH-1005 LAUSANNE,SWITZERLAND
关键词
cat; cortex; development; fluorescent tracers; neural connections;
D O I
10.1111/j.1460-9568.1990.tb00415.x
中图分类号
Q189 [神经科学];
学科分类号
071006 ;
摘要
The kitten's auditory cortex (including the first and second auditory fields Al and All) is known to send transient axons to either ipsi‐ or contralateral visual areas 17 and 18. By the end of the first postnatal month the transitory axons, but not their neurons of origin, are eliminated. Here we investigated where these neurons project after the elimination of the transitory axon. Eighteen kittens received early (postnatal day (pd) 2–5) injections of long lasting retrograde fluorescent traces in visual areas 17 and 18 and late (pd 35–64) injections of other retrograde fluorescent tracers in either hemisphere, mostly in areas known to receive projections from Al and All in the adult cat. The middle ectosylvian gyrus was analysed for double‐labelled neurons in the region corresponding approximately to Al and All. Late injections in the contralateral (to the analysed Al, All) hemisphere including all of the known auditory areas, as well as some visual and ‘association’ areas, did not relabel neurons which had had transient projections to either ipsi‐ or contralateral visual areas 17–18. Thus, Al and All neurons after eliminating their transient juvenile projections to visual areas 17 and 18 do not project to the other hemisphere. In contrast, relabelling was obtained with late injections in several locations in the ipsilateral hemisphere; it was expressed as per cent of the population labelled by the early injections. Few neurons (0–2.5%) were relabelled by large injections in the caudal part of the posterior ectosylvian gyrus and the adjacent posterior suprasylvian sulcus (areas DP, P, VP). Multiple injections in the middle ectosylvian gyrus relabelled a considerably larger percentage of neurons (13%). Single small injections in the middle ectosylvian gyrus (areas Al, All), the caudal part of the anterior ectosylvian gyrus and the rostral part of the posterior ectosylvian gyrus relabelled 3.1–7.0% of neurons. These neurons were generally near (< 2.0 mm) the outer border of the late injection sites. Neurons with transient projections to ipsi‐ or contralateral visual areas 17 and 18 were relabelled in similar proportions by late injections at any given location. Thus, Al or All neurons which send a transitory axon to ipsi‐ or contralateral visual areas 17 and 18 are most likely to form short permanent cortical connections. In that respect, they are similar to medial area 17 neurons that form transitory callosal axons and short permanent axons to ipsilateral visual areas 17 and 18. Copyright © 1990, Wiley Blackwell. All rights reserved
引用
收藏
页码:227 / 242
页数:16
相关论文
共 67 条
[41]  
KUYPERS HGJM, 1980, EXP BRAIN RES, V40, P383
[42]  
MARTIN KAC, 1983, EXP BRAIN RES, V50, P193
[43]   AN AUTORADIOGRAPHIC STUDY OF THE POSTNATAL-DEVELOPMENT OF SENSORIMOTOR AND VISUAL COMPONENTS OF THE CORTICOPONTINE SYSTEM [J].
MIHAILOFF, GA ;
ADAMS, CE ;
WOODWARD, DJ .
JOURNAL OF COMPARATIVE NEUROLOGY, 1984, 222 (01) :116-127
[44]  
MOONEY RD, 1984, EXP BRAIN RES, V55, P9
[45]   CORTICOCORTICAL CONNECTIONS OF THE CAT SENSORY AREAS STUDIED BY MEANS OF RETROGRADE AXONAL-TRANSPORT OF HORSERADISH-PEROXIDASE [J].
NAITO, J .
ARCHIVUM HISTOLOGICUM JAPONICUM, 1980, 43 (02) :99-114
[46]   EVIDENCE THAT THE EARLY POSTNATAL RESTRICTION OF THE CELLS OF ORIGIN OF THE CALLOSAL PROJECTION IS DUE TO THE ELIMINATION OF AXONAL COLLATERALS RATHER THAN TO THE DEATH OF NEURONS [J].
OLEARY, DDM ;
STANFIELD, BB ;
COWAN, WM .
DEVELOPMENTAL BRAIN RESEARCH, 1981, 1 (04) :607-617
[47]   OCCIPITAL CORTICAL-NEURONS WITH TRANSIENT PYRAMIDAL TRACT AXONS EXTEND AND MAINTAIN COLLATERALS TO SUBCORTICAL BUT NOT INTRACORTICAL TARGETS [J].
OLEARY, DDM ;
STANFIELD, BB .
BRAIN RESEARCH, 1985, 336 (02) :326-333
[48]   CORTICAL AND SUBCORTICAL AFFERENT CONNECTIONS OF A POSTERIOR DIVISION OF FELINE AREA-7 (AREA 7P) [J].
OLSON, CR ;
LAWLER, K .
JOURNAL OF COMPARATIVE NEUROLOGY, 1987, 259 (01) :13-30
[49]   THE COLLATERAL ORIGIN OF A TRANSIENT CEREBROCEREBELLAR PATHWAY IN KITTENS - A STUDY USING FLUORESCENT DOUBLE-LABELING TECHNIQUES [J].
PANNETON, WM ;
TOLBERT, DL .
DEVELOPMENTAL BRAIN RESEARCH, 1984, 14 (02) :247-254
[50]  
PAULABARBOSA MM, 1975, EXP BRAIN RES, V23, P535