Effects of dietary yeast nucleotides on growth, non-specific immunity, intestine growth and intestinal microbiota of juvenile hybrid tilapia Oreochromis niloticus female x Oreochromis aureus male

被引：65

作者：

Xu, Li ^{[1
]}

Ran, Chao ^{[1
]}

He, Suxu ^{[1
]}

Zhang, Jianli ^{[2
]}

Hu, Jun ^{[1
]}

Yang, Yalin ^{[1
]}

Du, Zhenyu ^{[3
]}

Yang, Yanou ^{[2
]}

Zhou, Zhigang ^{[1
]}

机构：

[1] Chinese Acad Agr Sci, Feed Res Inst, Minist Agr, Key Lab Feed Biotechnol, Beijing 100081, Peoples R China

[2] Anhui Agr Univ, Sci Anim & Technol Coll, Hefei 230036, Anhui, Peoples R China

[3] East China Normal Univ, Sch Life Sci, Shanghai 200062, Peoples R China

来源：

ANIMAL NUTRITION | 2015年 / 1卷 / 03期

基金：

中国国家自然科学基金;

关键词：

Nucleotides; Growth performance; Hybrid tilapia; Intestinal microbiota; Denaturing gradient gel electrophoresis;

D O I：

10.1016/j.aninu.2015.08.006

中图分类号：

S8 [畜牧、动物医学、狩猎、蚕、蜂];

学科分类号：

0905 ;

摘要：

This study investigated the effect of dietary supplementation of yeast nucleotides on the growth, nonspecific immunity, intestine growth and intestinal microbiota of juvenile hybrid tilapia. Tilapia (initial average weight of 8.02 g) was fed test diets supplemented with a yeast-originated nucleotide mixture (0, 0.15, 0.30, 0.60, and 1.20 g/100 g diet) for 8 weeks. Fish fed the diet with 0.60% nucleotide had significantly higher weight gain than the control group (P < 0.05). Feed efficiency was improved in the fish fed 0.60 and 1.20% nucleotide compared with that in the control group. The optimal doses of nucleotides supplementation for growth and feed efficiency of fish were determined as 0.63 and 0.81%, respectively. Intestinal growth was improved in the 0.30 and 0.60% groups, as indicated by significant increase in intestine length. The fish fed 0.60 and 1.20% nucleotide showed higher super oxide dismutase (SOD) activity and lower malondialdehyde (MDA) level in the liver than the control fish, indicating enhancement of the anti-oxidant status. Serum lysozyme activity was significantly increased in the 0.15 and 0.3% nucleotide supplementation groups, suggesting an enhancement effect on the non-specific immune response. Lastly, dietary nucleotides supplementation exerted moderate influence on the intestinal microbiota of hybrid tilapia. A reduction in the cumulative abundance of putative butyrate-producing species was observed in the intestinal microbiota of fish fed diets with 0.60% nucleotide compared with the control, implying an interaction between dietary nucleotides and butyrate production. Briefly, dietary supplementation with 0.60% nucleotide improve the growth performance, immune activity and intestine growth in tilapia. (C) 2015 Chinese Association of Animal Science and Veterinary Medicine. Production and hosting by Elsevier B.V. on behalf of KeAi Communications Co., Ltd.

引用

页码：244 / 251

页数：8

共 39 条

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