GC INSTRUMENTATION FOR ON-COLUMN INJECTION OF LARGE VOLUMES - AUTOMATED OPTIMIZATION OF CONDITIONS

Improved instrumentation facilitates on-column injection of up to several hundreds of microliters onto GC capillary columns. It incorporates an autosampler with adjustable injection speed, a standardized precolumn system, an early vapor exit, and software that models evaporation of a given solvent at the flow and temperature conditions chosen by the user. The software calculates the appropriate injection speed, guides the autosampler correspondingly, and closes the vapor exit at a moment leaving in the precolumn the amount of unevaporated solvent that is selected by the user. (C) 1995 John Wiley & Sons, Inc.