IGG AND IGM RHEUMATOID-FACTOR LEVELS PARALLEL INTERLEUKIN-6 DURING THE VASCULITIC PHASE IN A PATIENT WITH CHURG-STRAUSS-SYNDROME

被引：10

作者：

YOKOYAMA, A

KOHNO, N

FUJINO, S

INOUE, Y

HIWADA, K

机构：

[1] The Second Department of Internal Medicine, Ehime University, School of Medicine, Ehime

来源：

INTERNAL MEDICINE | 1995年 / 34卷 / 07期

关键词：

AUTOANTIBODY; CYTOKINE; SYSTEMIC ANGITIS;

D O I：

10.2169/internalmedicine.34.646

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

A 43-year-old woman with a 10-year history of bronchial asthma developed marked peripheral blood eosinophilia and symptoms of vasculitis. A diagnosis of Churg-Strauss syndrome (CSS) was made, and her symptoms were successfully treated with low-dose prednisolone. Serum rheumatoid factors (RF) of both IgG and IgM, but not IgA or IgE, subclasses transiently appeared in accordance with the vasculitic phase, Serum interleukin-6 (IL-6) levels also transiently increased in this phase, and the peak level was reached just prior to the maximum of RF elevation, suggesting the role of IL-6 as an inducer of RF, RF and IL-6 seemed to be involved in the pathogenesis of the vasculitis in this patient.

引用

页码：646 / 648

页数：3

共 10 条

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