NEONATAL HEMOCHROMATOSIS ASSOCIATED WITH MATERNAL AUTOANTIBODIES AGAINST RO/SS-A AND LA/SS-B RIBONUCLEOPROTEINS

被引：40

作者：

SCHOENLEBE, J

BUYON, JP

ZITELLI, BJ

FRIEDMAN, D

GRECO, MA

KNISELY, AS

机构：

[1] CHILDRENS HOSP PITTSBURGH,DEPT PATHOL,3705 5TH AVE,PITTSBURGH,PA 15213

[2] STADT KLINIKUM DRESDEN,INST PATHOL GEORG SCHMORL,DRESDEN,GERMANY

[3] NYU MED CTR,DEPT MED,DIV RHEUMATOL,NEW YORK,NY 10016

[4] NYU MED CTR,DEPT PATHOL,NEW YORK,NY 10016

[5] NYU,HOSP JOINT DIS,SCH MED,DEPT RHEUMAT DIS & MOLEC MED,NEW YORK,NY 10003

[6] RITA & STANLEY KAPLAN CANC CTR,NEW YORK,NY

[7] CHILDRENS HOSP PITTSBURGH,DEPT PEDIAT,PITTSBURGH,PA 15213

[8] UNIV PITTSBURGH,PITTSBURGH,PA 15260

来源：

AMERICAN JOURNAL OF DISEASES OF CHILDREN | 1993年 / 147卷 / 10期

关键词：

D O I：

10.1001/archpedi.1993.02160340058014

中图分类号：

R72 [儿科学];

学科分类号：

100202 ;

摘要：

Liver disease in the fetus and neonate may be associated with maternal Sjogren's syndrome (neonatal lupus erythematosus). The infant of a mother with Sjogren's syndrome and high anti-Ro/SS-A and anti-La/SS-B antibody titers presented at 2 1/2 weeks of age with overwhelming hepatic insufficiency and died at 6 weeks of age. Autopsy confirmed the antemortem diagnosis of neonatal hemochromatosis. We discuss the possibility of a relationship between these two conditions.

引用

页码：1072 / 1075

页数：4

共 14 条

[1] ISOLATION AND CHARACTERIZATION OF A CDNA CLONE ENCODING THE 60-KD COMPONENT OF THE HUMAN SS-A/RO RIBONUCLEOPROTEIN AUTO-ANTIGEN [J].