The role of the microenvironment in tumor immune surveillance

被引：12

作者：

Oluwadara, Oluwadayo ^{[1
]}

Giacomelli, Luca ^{[2
]}

Brant, Xenia ^{[1
,3
]}

Christensen, Russell ^{[4
]}

Avezova, Raisa ^{[1
]}

Kossan, George ^{[1
]}

Chiappelli, Francesco ^{[1
]}

机构：

[1] Sch Dent, Div Oral Biol & Med, Lido Di Camaiore, Lucca, Italy

[2] Tirrenian Stomatol Inst, Lido Di Camaiore, Lucca, Italy

[3] CEO IPSEMG Belo Horizonte, Belo Horizonte, MG, Brazil

[4] Univ Calif Los Angeles, Sch Dent, Div Oral & Maxillofacial Pathol, Los Angeles, CA 90024 USA

来源：

BIOINFORMATION | 2011年 / 5卷 / 07期

关键词：

Oral lichen planus; oral squamous cell carcinoma; proteomic voting; tumor microenvironment; T cell lineages; tumor immune surveillance;

D O I：

10.6026/97320630005285

中图分类号：

Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

The evidence appears compelling that the microenvironment, and associated biological cellular and molecular factors, may contribute to the progression of a variety of tumors. The effects of the microenvironment may directly influence the plasticity of T cell lineages, which was recently discussed (O'Shea & Paul, 2010 [4]). To review the putative role of the microenvironment in modulating the commitment of tumor immune surveillance, we use the model of oral premalignant lesions.

引用

页码：285 / 290

页数：6

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