Predicting receptor-ligand interactions

被引：9
|
作者：
Burt, Stanley K. [1 ]
Hutchins, Charles W. [1 ]
Greer, Jonathan [1 ]
机构：
[1] Abbott Labs, Comp Assisted Mol Design Grp, Abbott Pk, IL 60064 USA
来源：
CURRENT OPINION IN STRUCTURAL BIOLOGY | 1991年 / 1卷 / 02期
关键词：
D O I：
10.1016/0959-440X(91)90063-Y
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Advances in computational methodology and increased structural information about receptors have increased our ability to model and predict ligand receptor interactions. This review summarizes current computational methods used to develop models of ligand receptor complexes and new methods that can use these structural models to discover novel ligands.
引用
收藏
页码：213 / 218
页数：6
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