A MILD AND CONVENIENT METHOD FOR TRITIUM LABELING OF ACTIVATED AROMATIC-COMPOUNDS USING BF3-ET2O AND TRITIATED-WATER

被引：7

作者：

MCGEADY, P ^{[1
]}

CROTEAU, R ^{[1
]}

机构：

[1] WASHINGTON STATE UNIV,INST BIOL CHEM,PULLMAN,WA 99164

来源：

JOURNAL OF THE CHEMICAL SOCIETY-CHEMICAL COMMUNICATIONS | 1993年 / 09期

关键词：

D O I：

10.1039/c39930000774

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A procedure for tritium exchange labelling of activated aromatic compounds using (H2O)-H-3 and BF3-Et2O has been developed to prepare two radio-labelled photoprobes that are difficult to obtain by conventional methods; the applicability of the method has been examined by labelling several aromatic compounds varying in activation toward electrophilic aromatic substitution.

引用

页码：774 / 776

页数：3

共 13 条

[1] ARMSTRONG AP, 1988, FASEB J, pA563
[2] CLARKE HT, 1941, ORG SYNTH, V1, P514
[3] DOX AW, 1941, ORG SYNTH, V1, P5
[4] 3-(TRIFLUOROMETHYL)-3-(M-[I-125]IODOPHENYL)DIAZIRINE PHOTOLABELS A SUBSTRATE-BINDING SITE OF RAT HEPATIC CYTOCHROME-P-450 FORM PB-4
FREY, AB
KREIBICH, G
WADHERA, A
CLARKE, L
WAXMAN, DJ
[J]. BIOCHEMISTRY, 1986, 25 (17) : 4797 - 4803
[5] HALOGENATION OF AMIDINES .I. SYNTHESIS OF 3-HALO- AND OTHER NEGATIVELY SUBSTITUTED DIAZIRINES
GRAHAM, WH
[J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1965, 87 (19) : 4396 - &
[6] MONOTERPENE BIOSYNTHESIS - SPECIFICITY OF THE HYDROXYLATIONS OF (-)-LIMONENE BY ENZYME PREPARATIONS FROM PEPPERMINT (MENTHA-PIPERITA), SPEARMINT (MENTHA-SPICATA), AND PERILLA (PERILLA-FRUTESCENS) LEAVES
KARP, F
MIHALIAK, CA
HARRIS, JL
CROTEAU, R
[J]. ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, 1990, 276 (01) : 219 - 226
[7] CONVENIENT PREPARATION OF DEUTERATED AROMATIC-COMPOUNDS
LARSEN, JW
CHANG, LW
[J]. JOURNAL OF ORGANIC CHEMISTRY, 1978, 43 (18) : 3602 - 3602
[8] RAPID DEUTERIATION AND TRITIATION OF ORGANIC COMPOUNDS USING ORGANOMETALLIC AND ELEMENTAL HALIDES AS CATALYSTS
LONG, MA
GARNETT, JL
VINING, RFW
[J]. JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 2, 1975, (12): : 1298 - 1303
[9] LONG MA, 1978, TETRAHEDRON LETT, P4174
[10] TRITIATION OF AROMATICS BY HTO-PROMOTED ALUMINUM CHLORIDE
MANTESCU, C
BALABAN, AT
[J]. CANADIAN JOURNAL OF CHEMISTRY-REVUE CANADIENNE DE CHIMIE, 1963, 41 (08): : 2120 - &

← 1 2 →