GENE CLUSTERS ENCODING THE CYTOTOXIC NECROTIZING FACTOR TYPE-1, PRS-FIMBRIAE AND ALPHA-HEMOLYSIN FORM THE PATHOGENICITY ISLAND-II OF THE UROPATHOGENIC ESCHERICHIA-COLI STRAIN-J96

被引：18

作者：

BLUM, G ^{[1
]}

FALBO, V ^{[1
]}

CAPRIOLI, A ^{[1
]}

HACKER, J ^{[1
]}

机构：

[1] IST SUPER SANITA, ULTRASTRUTTURE LAB, I-00161 ROME, ITALY

来源：

FEMS MICROBIOLOGY LETTERS | 1995年 / 126卷 / 02期

关键词：

PATHOGENICITY ISLANDS; UROVIRULENCE; HEMOLYSIN; P-FIMBRIAE; ESCHERICHIA COLI; CYTOTOXIC NECROTIZING FACTOR 1;

D O I：

10.1111/j.1574-6968.1995.tb07415.x

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

The uropathogenic Escherichia coli strain J96 (04:K6) is able to produce four adherence factors [P-fimbriae (pap and prs), F1C-fimbriae (foe) and Type 1-fimbriae (fim)], two alpha-hemolysins (hlyI and II) and the cytotoxic necrotizing factor type 1 (cnf1). Using phenotypic test systems and genotypic analysis, it has been shown that the mutant strain J96-M1 has lost the hlyII, prs and cnf1 genes. The three virulence associated determinants are linked on one particular region on the chromosome, which is termed 'pathogenicity island II' (Pai II).

引用

页码：189 / 195

页数：7

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