Survey of the level of anti-HBs antibody titer in vaccinated Iranian general dentists

被引:22
作者
Alavian, Seyed-Moayed [1 ,2 ]
Izadi, Morteza [3 ]
Zare, Ali-Akbar [4 ]
Lankarani, Maryam [5 ]
Assari, Shervin [4 ]
Vardi, Mohammad-Mahdi [2 ]
机构
[1] Baqiyatallah Res Ctr Gastroenterol & Liver Dis, Tehran, Iran
[2] Minist Hlth, Tehran, Iran
[3] Baqiyatallah Univ Med Sci, Hlth Res Ctr, Tehran, Iran
[4] Baqiyatallah Univ Med Sci, Clin Res Unit, Tehran, Iran
[5] Islamic Azad Univ, Tehran Med Unit, Tehran, Iran
关键词
Hepatitis B; antibody titer; vaccination; general dentists;
D O I
10.1111/j.1754-4505.2008.00052.x
中图分类号
R78 [口腔科学];
学科分类号
1003 ;
摘要
Hepatitis B is an infectious disease to which dentists are susceptible. The main aim of this study was to determine the level of antibody titer and immunity in vaccinated Iranian general dentists. A total of 861 general dentists were invited to participate in this study; 598 persons who could recall their history of vaccination and consented to have blood samples taken were recruited. Demographic and work-related data were recorded, and anti-Hepatitis B surface antigen (anti-HBs-Ag) evaluations were measured using the enzyme-linked immunosorbent assay (ELISA). Of the 598 participants, 35 (5.9%) were nonimmune (anti-HBs < 10 IU/l), 101 (16.9%) were relatively immune (antiHBs = 10-99 IU/l), and 462 (77.3%) were completely immune (anti-HBs >= 100 IU/l). Only 218 (36.5%) of the dentists knew their HBs antibody titer. Fourteen (2.3%) persons reported receiving one dose and 65 (10.9%) had received two doses. The number of those who had received the three recommended doses totaled 519 (86.8%), 491 (82.1%) of them receiving their vaccine on schedule. Age, city, pack-years of smoking, years of smoking, and the interval between the last vaccination and the commencement of the study had a significant relationship to the antibody titer level, whereas sex, marital status, place of practice, smoking, and vaccination schedule were not related. Only 36.5% of the general dentists had checked their antibody titer. We, therefore, recommend that dentists, as a potential high-risk group, should know their level of anti-HBs antibody titer so that those who require revaccination can get treatment.
引用
收藏
页码:265 / 270
页数:6
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