HYPER-URICEMIA ASSOCIATED WITH HYPERTENSION A 4-YEAR FOLLOW-UP-STUDY OF HYPERURICEMIC HYPERTENSIVES

被引：4
作者：
TOFUKU, Y
KURODA, M
TAKEDA, R
机构：
[1] The 2nd Department of Internal Medicine, Kanazawa University, School of Medicine, Kanazawa
来源：
JAPANESE CIRCULATION JOURNAL-ENGLISH EDITION | 1978年 / 42卷 / 07期
关键词：
Cerebrovascular disease; Essential hypertension; Hyperuricemia; Myocardial infarction; Risk factor;
D O I：
10.1253/jcj.42.871
中图分类号：
N09 [自然科学史]; B [哲学、宗教];
学科分类号：
01 ; 0101 ; 010108 ; 060207 ; 060305 ; 0712 ;
摘要：
We investigated the prognosis of 153 hypertensive patients, whose initial concentration of serum uric acid had been evaluated. One hundred and seventeen subjects could be followed up after 4 years and 16 of them died during the follow-up period. Cerebrovascular disease was seen in 6 subjects, 4 of whom died from the disease. Myocardial infarction and heart failure occurred in 9 and 7 of them died as a result. The frequency of these diseases was greater among the hyperuricemic group and 8 of the 11 who died belonged to this group. Four men were struck by gouty attacks. They were all hyperuricemic and had been proven to have at least one family member with asymptomatic hyperuricemia and/or gout. It is reasonable to regard the presence of hyperuricemia as one of the poor risk factors for vascular diseases. In addition, we must investigate more closely personal and family histories of gout when we see hyperuricemic subjects, regardless of absence of gouty symptoms. © 1978, The Japanese Circulation Society. All rights reserved.
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页码：871 / 879
页数：9
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