SOME IMMUNOLOGICAL INDEXES IN PATIENTS WITH CHRONIC MYELOLEUCOSIS IN THE STAGE OF BLAST CRISIS

Twenty patients with chronic myeloleucosis in the stage of blast crisis were examined. Results of immunological investigations indicate that these patients showed below normal indices of the absorptive and bactericidal function of polymorphous-nuclear neutrophils and cationic proteins. The number of T- and B-lymphocytes was also reduced. The immunity values were to the same degree inhibited as in patients with acute leucosis. Changes of the immune status depend on the degree of blastemia. Along with cytostatic agents patients with chronic myeloleucosis in the stage of blast crisis should undergo immunocorrection, primarily correction of cellular imunity.