SELECTIVITY OF SEROTONERGIC DRUGS FOR MULTIPLE BRAIN-SEROTONIN RECEPTORS - ROLE OF [H-3] 4-BROMO-2,5-DIMETHOXYPHENYLISOPROPYLAMINE ([H-3]DOB), A 5-HT2 AGONIST RADIOLIGAND

被引:143
作者
TITELER, M [1 ]
LYON, RA [1 ]
DAVIS, KH [1 ]
GLENNON, RA [1 ]
机构
[1] VIRGINIA COMMONWEALTH UNIV,DEPT MED CHEM,RICHMOND,VA 23284
关键词
D O I
10.1016/0006-2952(87)90643-5
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
引用
收藏
页码:3265 / 3271
页数:7
相关论文
共 33 条
[1]   IPSAPIRONE DEPRESSES NEURONAL-ACTIVITY IN THE DORSAL RAPHE NUCLEUS AND THE HIPPOCAMPAL-FORMATION [J].
BASSETOMUSK, A ;
REBEC, GV .
EUROPEAN JOURNAL OF PHARMACOLOGY, 1986, 130 (1-2) :141-143
[2]   GUANYL NUCLEOTIDE AND DIVALENT-CATION REGULATION OF CORTICAL-S2 SEROTONIN RECEPTORS [J].
BATTAGLIA, G ;
SHANNON, M ;
TITELER, M .
JOURNAL OF NEUROCHEMISTRY, 1984, 43 (05) :1213-1219
[3]  
BRADY LS, 1985, J PHARMACOL EXP THER, V235, P436
[4]  
DESOUZA RJ, 1986, BRIT J PHARMACOL, V89, P377
[5]   H-3-TVX Q-7821 - IDENTIFICATION OF 5-HT1 BINDING-SITES AS TARGET FOR A NOVEL PUTATIVE ANXIOLYTIC [J].
DOMPERT, WU ;
GLASER, T ;
TRABER, J .
NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY, 1985, 328 (04) :467-470
[6]   BIOCHEMICAL ASSESSMENT OF THE CENTRAL 5-HT AGONIST ACTIVITY OF RU-24969 (A PIPERIDINYL INDOLE) [J].
EUVRARD, C ;
BOISSIER, JR .
EUROPEAN JOURNAL OF PHARMACOLOGY, 1980, 63 (01) :65-72
[7]  
FRIEDMAN RL, 1984, J PHARMACOL EXP THER, V228, P628
[8]   5-HT1 AND 5-HT2 BINDING CHARACTERISTICS OF SOME QUIPAZINE ANALOGS [J].
GLENNON, RA ;
SLUSHER, RM ;
LYON, RA ;
TITELER, M ;
MCKENNEY, JD .
JOURNAL OF MEDICINAL CHEMISTRY, 1986, 29 (11) :2375-2380
[9]   DOM-STIMULUS GENERALIZATION TO LSD AND OTHER HALLUCINOGENIC INDOLEALKYLAMINES [J].
GLENNON, RA ;
YOUNG, R ;
JACYNO, JM ;
SLUSHER, M ;
ROSECRANS, JA .
EUROPEAN JOURNAL OF PHARMACOLOGY, 1983, 86 (3-4) :453-459
[10]   EVIDENCE FOR 5-HT2 INVOLVEMENT IN THE MECHANISM OF ACTION OF HALLUCINOGENIC AGENTS [J].
GLENNON, RA ;
TITELER, M ;
MCKENNEY, JD .
LIFE SCIENCES, 1984, 35 (25) :2505-2511