PROTECTION BY N-ACETYLCYSTEINE OF CYCLOPHOSPHAMIDE METABOLISM-RELATED INVIVO DEPRESSION OF MIXED-FUNCTION OXYGENASE ACTIVITY AND INVITRO DENATURATION OF CYTOCHROME-P-450

被引：31
作者：
BERRIGAN, MJ
GURTOO, HL
SHARMA, SD
STRUCK, RF
MARINELLO, AJ
机构：
[1] NEW YORK STATE DEPT HLTH,ROSWELL PK MEM INST,GRACO CANC DRUG CTR,BUFFALO,NY 14263
[2] SO RES INST,BIRMINGHAM,AL 35205
[3] NEW YORK STATE DEPT HLTH,ROSWELL PK MEM INST,DEPT EXPTL THERAPEUT,BUFFALO,NY 14263
来源：
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS | 1980年 / 93卷 / 03期
关键词：
D O I：
10.1016/0006-291X(80)91147-X
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
引用
收藏
页码：797 / 803
页数：7
相关论文
共 14 条
[1]  
BROCK N, 1979, ARZNEIMITTEL-FORSCH, V29-1, P659
[2]  
BROCK N, 1963, ARZNEIMITTEL-FORSCH, V13, P1021
[3]   PHOTOCHEMICAL ACTION SPECTRUM OF TERMINAL OXIDASE OF MIXED FUNCTION OXIDASE SYSTEMS [J].
COOPER, DY ;
LEVIN, S ;
NARASIMHULU, S ;
ROSENTHAL, O ;
ESTABROOK, RW .
SCIENCE, 1965, 147 (3656) :400-+
[4]   CYCLOPHOSPHAMIDE CYSTITIS - IDENTIFICATION OF ACROLEIN AS THE CAUSATIVE AGENT [J].
COX, PJ .
BIOCHEMICAL PHARMACOLOGY, 1979, 28 (13) :2045-2049
[5]  
DRAEGER U, 1976, CANCER TREAT REP, V60, P355
[6]  
GURTOO HL, 1976, CANCER TREAT REP, V60, P1285
[7]   EFFECT OF N-ACETYLCYSTEINE ON SOME ASPECTS OF CYCLOPHOSPHAMIDE-INDUCED TOXICITY AND IMMUNOSUPPRESSION [J].
LEVY, L ;
HARRIS, R .
BIOCHEMICAL PHARMACOLOGY, 1977, 26 (11) :1015-1020
[8]  
LOWRY OH, 1951, J BIOL CHEM, V193, P265
[9]   DENATURATION OF CYTOCHROME-P-450 BY CYCLOPHOSPHAMIDE METABOLITES [J].
MARINELLO, AJ ;
GURTOO, HL ;
STRUCK, RF ;
PAUL, B .
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1978, 83 (04) :1347-1353
[10]  
NEBERT DW, 1968, J BIOL CHEM, V243, P6242
12