HPLC WITH CARBOHYDRATE CARBAMATE CHIRAL PHASES - INFLUENCE OF CHIRAL PHASE-STRUCTURE ON ENANTIOSELECTIVITY

被引：65
作者：
MATLIN, SA
TIRITAN, ME
CRAWFORD, AJ
CASS, QB
BOYD, DR
机构：
[1] UNIV FED SAO CARLOS,DEPT CHEM,SAO CARLOS,SP,BRAZIL
[2] QUEENS UNIV BELFAST,SCH CHEM,BELFAST,ANTRIM,NORTH IRELAND
来源：
CHIRALITY | 1994年 / 6卷 / 02期
关键词：
AMYLOSE; CELLULOSE; PHENYLCARBAMATE; 3,5-DIMETHYLPHENYLCARBAMATE; 3,5-DIMETHOXYPHENYLCARBAMATE; TRANS-STILBENE OXIDE; CHIRAL SULFOXIDES; RESOLUTION;
D O I：
10.1002/chir.530060214
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
The enantioselective resolution of trans-stilbene oxide and of 23 chiral sulfoxides was investigated on cellulose and amylose tris(arylcarbamate) stationary phases coated on aminopropylated 7 mu m spherical silica with 500 Angstrom diameter pores. Cellulose tris-(3,5 dimethylphenylcarbamate) showed good resolving power for many of the sulfoxides and amylose tris-(3,5 dimethoxyphenylcarbamate) showed advantages for the resolution of certain sulfoxides which were not separated on other phases. (C) 1994 Wiley-Liss, Inc.
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页码：135 / 140
页数：6
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