CYTOKINE PRODUCTION BY MAST-CELLS AND BASOPHILS

被引：314

作者：

GALLI, SJ ^{[1
]}

GORDON, JR ^{[1
]}

WERSHIL, BK ^{[1
]}

机构：

[1] HARVARD UNIV, SCH MED, BOSTON, MA 02115 USA

来源：

CURRENT OPINION IN IMMUNOLOGY | 1991年 / 3卷 / 06期

关键词：

D O I：

10.1016/S0952-7915(05)80005-6

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Mast cells and/or basophils have been implicated in the expression of a wide variety of biological responses, including immediate hypersensitivity reactions, host responses to parasites and neoplasms, angiogenesis, tissue remodeling, and immunologically non-specific inflammatory and fibrotic conditions. Recent findings suggest that an important mechanism by which mast cells influence such biological responses is through the production of a broad panel of multifunctional cytokines. In contrast, the extent to which basophils can produce cytokines is uncertain.

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页码：865 / 873

页数：9

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