Hepatitis B virus reactivation with rituximab-containing regimen

被引:21
作者
Tsutsumi, Yutaka [1 ]
Yamamoto, Yoshiya [2 ]
Shimono, Joji [1 ]
Ohhigashi, Hiroyuki [1 ]
Teshima, Takanori [3 ]
机构
[1] Hakodate Municipal Hosp, Dept Hematol, Hakodate 1-10-1,Minato Cho, Hakodate, Hokkaido 0418680, Japan
[2] Hakodate Municipal Hosp, Dept Gastroenterol, Hakodate, Hokkaido 0418680, Japan
[3] Hokkaido Univ, Grad Sch Med, Dept Hematol, JIS-01663 Sapporo, Hokkaido, Japan
关键词
Rituximab; Hepatitis B virus; Reactivation; Chemotherapy; Lamivudine; Non-Hodgkin's lymphoma;
D O I
10.4254/wjh.v5.i11.612
中图分类号
R57 [消化系及腹部疾病];
学科分类号
摘要
Rituximab is recognized as a useful drug for the treatment of B-cell non-Hodgkin's lymphoma and its use has been extended to such diseases as idiopathic thrombocytopenic purpura, thrombotic thrombocytopenic purpura, chronic rheumatoid arthritis and AN-CA-associated vasculitides. One serious complication associated with its use is the reactivation of hepatitis B virus and the search for methods to prevent this occurrence has resulted in the rapid accumulation of knowledge. In this review, we discuss case analyses from our department and other groups and outline the current knowledge on the topic and the remaining issues. (C) 2013 Baishideng Publishing Group Co., Limited. All rights reserved.
引用
收藏
页码:612 / 620
页数:9
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