Anti-inflammatory therapy for asthma

被引:0
作者
Pawliczak, Rafal [1 ]
机构
[1] Uniwersytet Med Lodzi, Katedra Alergol Immunol & Dermatol, Ul Zeligowskiego 7-9 Bud II Pok 122, PL-90752 Lodz, Poland
关键词
Asthma; Inflammation; Glucocorticoids;
D O I
10.1016/j.alergo.2014.03.007
中图分类号
R392 [医学免疫学];
学科分类号
100102 ;
摘要
Treatment of asthma has changed over the years. Despite these changes, since the middle of last century many managed to get a consensus to focus the anti-asthma therapy on inflammatory processes. The primary anti-inflammatory medicines for asthma are inhaled glucocorticoids. This paper showed clinical data on inflammation in asthma and summarized the knowledge of novel glucocorticoids used in inhaled asthma therapy. It also highlighted the differences between substances. Currently glucocorticoids are characterized by a very high safety profile and a lot of different inhalation systems. The study highlighted the need to make rational therapeutical choices and proper selection of the drug for the individual patient. (C) 2014 Polish Society of Allergology. Published by Elsevier Urban & Partner Sp. z o. o. All rights reserved.
引用
收藏
页码:38 / 42
页数:5
相关论文
共 53 条
  • [1] Relative oral corticosteroid-sparing effect of 7 inhaled corticosteroids in chronic asthma: a meta-analysis
    Abdullah, Anwar K.
    Khan, Salman
    [J]. ANNALS OF ALLERGY ASTHMA & IMMUNOLOGY, 2008, 101 (01) : 74 - 81
  • [2] Evidence-based selection of inhaled corticosteroid for treatment of chronic asthma
    Abdullah, Anwar K.
    Khan, Salman
    [J]. JOURNAL OF ASTHMA, 2007, 44 (01) : 1 - 12
  • [3] Inhaled fluticasone furoate/vilanterol does not affect hypothalamic-pituitary-adrenal axis function in adolescent and adult asthma: randomised, double-blind, placebo-controlled study
    Allen, Ann
    Schenkenberger, Isabelle
    Trivedi, Roopa
    Cole, Jeremy
    Hicks, Wesley
    Gul, Nadeem
    Jacques, Loretta
    [J]. CLINICAL RESPIRATORY JOURNAL, 2013, 7 (04) : 397 - 406
  • [4] [Anonymous], 2012, MMW Fortschr Med, V154, P70
  • [5] [Anonymous], 2005, Med Lett Drugs Ther, V47, P98
  • [6] Antoniu SA, 2009, EXPERT OPIN PHARMACO, V10, P917, DOI [10.1517/14656560902824160, 10.1517/14656560902824160 ]
  • [7] Effects of mometasone furoate on the quality of life: a randomized placebo-controlled trial in persistent allergic rhinitis and intermittent asthma using the Rhinasthma questionnaire
    Baiardini, I.
    Villa, E.
    Rogkakou, A.
    Pellegrini, S.
    Bacic, M.
    Compalati, E.
    Braido, F.
    Le Grazie, C.
    Canonica, G. W.
    Passalacqua, G.
    [J]. CLINICAL AND EXPERIMENTAL ALLERGY, 2011, 41 (03) : 417 - 423
  • [8] Inhaled corticosteroids for asthma: are they all the same?
    Baptist, A. P.
    Reddy, R. C.
    [J]. JOURNAL OF CLINICAL PHARMACY AND THERAPEUTICS, 2009, 34 (01) : 1 - 12
  • [9] Comparison of twice-daily inhaled ciclesonide and fluticasone propionate in patients with moderate-to-severe persistent asthma
    Bateman, E. D.
    Linnhof, A. E.
    Homik, L.
    Freudensprung, U.
    Smau, L.
    Engelstaetter, R.
    [J]. PULMONARY PHARMACOLOGY & THERAPEUTICS, 2008, 21 (02) : 264 - 275
  • [10] Randomized comparison of ciclesonide 160 and 640 μg/day in severe asthma
    Bateman, E. D.
    Cheung, D.
    Lapa e Silva, J.
    Goehring, U. M.
    Schaefer, M.
    Engelstaetter, R.
    [J]. PULMONARY PHARMACOLOGY & THERAPEUTICS, 2008, 21 (03) : 489 - 498