irritable bowel syndrome (iBs) is a common functional gastrointestinal disorder that typically affects adults between the ages of 30 and 50 years, with female predominance. its hallmark features include abdominal discomfort, bloating, and abnormal defecation, which may be constipation or diarrhea predominant. iBs is difficult to diagnose and does not have an established cure at this time. currently, treatment strategies are patient specific, focusing on symptom control and improvement in quality of life. nonpharmacologic options such as exclusion diets, dietary changes, peppermint oil, exercise, relaxation therapy, or acupuncture have been evaluated. pharmacologic therapy includes antidiarrheals, laxatives, probiotics, anticholinergics, antidepressants, antibiotics, and the newly approved drug linaclotide. new treatment options are also currently in the pipeline. pharmacists can play an important role in assisting the patient with iBs, as they are easily accessible health care professionals.