Aggressive cutaneous zygomycosis caused by Apophysomyces variabilis in an immunocompetent child

被引：12

作者：

Al-Zaydani, Ibrahim A. ^{[1
]}

Al-Hakami, Ahmed M. ^{[2
]}

Joseph, Martin R. P. ^{[2
]}

Kassem, Walid M. ^{[3
]}

Almaghrabi, Mohamed K. ^{[2
]}

Nageeb, Abdalla ^{[2
]}

Hamid, Mohamed E. ^{[2
]}

机构：

[1] Aseer Cent Hosp, Dept Pediat, Abha, Saudi Arabia

[2] King Khalid Univ, Coll Med, Dept Clin Microbiol & Parasitol, Abha, Saudi Arabia

[3] Aseer Cent Hosp, Dept Surg, Abha, Saudi Arabia

来源：

MEDICAL MYCOLOGY CASE REPORTS | 2015年 / 10卷

关键词：

Zygomycetes; Apophysomyces; Amputation; 28S rRNA gene; Aseer region;

D O I：

10.1016/j.mmcr.2015.12.003

中图分类号：

R-3 [医学研究方法]; R3 [基础医学];

学科分类号：

1001 ;

摘要：

A zygomycetous fungus was observed in a biopsy of a 9-year-old male. The patient was presented with severe cutaneous lesions subsequent to a traumatic car accident. Following fungal detection, antifungal treatment was prescribed but condition deteriorated rapidly and above knee amputation was done as lifesaving and to control fungal infection. Analysis of the 28 S rRNA gene (accession KT149770) aligned the isolate with members of the genus Apophysomyces and the pathogen was identified as Apophysomces variabilis. (C) 2015 The Authors. International Society for Human and Animal Mycology Published by Elsevier B.V. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

引用

页码：11 / 13

页数：3

共 16 条

[1] ZYGOMYCETE SAKSENAEA-VASIFORMIS AS A PATHOGEN OF HUMANS WITH A CRITICAL-REVIEW OF ETIOLOGY OF ZYGOMYCOSIS [J].

AJELLO, L ;

DEAN, DF ;

IRWIN, RS .

MYCOLOGIA, 1976, 68 (01) :52-62

[2] Post-traumatic Lethal Form of Primary Cutaneous Zygomycosis in a Healthy Young Patient and Review of the Literature [J].

Al Barrag, Mohamed Khalid ;

Al Zobydi, Abdu Hassan ;

Al Hazmi, Mohamed Mohamed ;

Mikhail, Nabil Tadros ;

Bakrain, Mohamed Yahia ;

Alsiddiky, Abdulmonem Mohamed .

JOURNAL OF TAIBAH UNIVERSITY MEDICAL SCIENCES, 2009, 4 (02) :162-169

[3] Cutaneous zygomycosis due to Saksenaea vasiformis:: Case report and literature review [J].

Al-Hedaithy, M .

ANNALS OF SAUDI MEDICINE, 1998, 18 (05) :428-431

[4] Cutaneous zygomycosis [J].

Bonifaz, Alexandro ;

Vazquez-Gonzalez, Denisse ;

Tirado-Sanchez, Andres ;

Maria Ponce-Olivera, Rosa .

CLINICS IN DERMATOLOGY, 2012, 30 (04) :413-419

[5] Invasive Apophysomyces variabilis Infection in a Burn Patient [J].

dela Cruz, Wilfred P. ;

Calvano, Tatjana P. ;

Griffith, Matthew E. ;

White, Christopher E. ;

Kim, Seung H. ;

Sutton, Deanna A. ;

Thompson, Elizabeth H. ;

Fu, Jianmin ;

Wickes, Brian L. ;

Guarro, Josep ;

Hospenthal, Duane R. .

JOURNAL OF CLINICAL MICROBIOLOGY, 2012, 50 (08) :2814-2817

[6]

Edlich Richard F, 2005, J Long Term Eff Med Implants, V15, P57, DOI 10.1615/JLongTermEffMedImplants.v15.i1.70

[7]

Ellis D., 2014, MYCOLOGY ONLINE IDEN, P5005

[8] In vitro antifungal activities of voriconazole and reference agents as determined by NCCLS methods: Review of the literature [J].

Espinel-Ingroff, A ;

Boyle, K ;

Sheehan, DJ .

MYCOPATHOLOGIA, 2001, 150 (03) :101-115

[9] Differentiation of anaerobic polycentric fungi by rDNA PCR-RFLP [J].

Fliegerova, K. ;

Mrazek, J. ;

Voigt, K. .

FOLIA MICROBIOLOGICA, 2006, 51 (04) :273-277

[10] Apophysomyces variabilis Infections in Humans [J].

Guarro, Josep ;

Chander, Jagdish ;

Alvarez, Eduardo ;

Stchigel, Alberto M. ;

Robin, Kaushik ;

Dalal, Usha ;

Rani, Hena ;

Punia, Rajpal S. ;

Cano, Jose F. .

EMERGING INFECTIOUS DISEASES, 2011, 17 (01) :134-135

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