Bilateral Renal Infarction due to MTHFR C677T Mutation and Hyperhomocysteinemia

被引：0

作者：

Guzel, Fatma Betul ^{[1
]}

Senel, Egemen ^{[1
]}

Ocal, Fatih ^{[2
]}

Kizildag, Betul ^{[3
]}

Erken, Ertugrul ^{[1
]}

Altunoren, Orcun ^{[1
]}

Gungor, Ozkan ^{[1
]}

机构：

[1] Kahramanmaras Sutcu Imam Univ, Tip Fak, Nefrol Bilim Dali, Kahramanmaras, Turkey

[2] Kahramanmaras Sutcu Imam Univ, Tip Fak, Hematol Anabilim Dali, Kahramanmaras, Turkey

[3] Kahramanmaras Sutcu Imam Univ, Tip Fak, Radyol Anabilim Dali, Kahramanmaras, Turkey

来源：

TURKISH NEPHROLOGY DIALYSIS AND TRANSPLANTATION JOURNAL | 2018年 / 27卷 / 03期

关键词：

Renal infarct; Homocysteine; MTHFR C677;

D O I：

10.5262/tndt.2018.2971

中图分类号：

R5 [内科学]; R69 [泌尿科学（泌尿生殖系疾病）];

学科分类号：

1002 ; 100201 ;

摘要：

Renal infarction is a condition induced by renal artery occlusion and causes renal parenchymal damage. The most common cause of renal infarction is atheroembolic cardiac diseases. Other causes are trauma, autoimmune diseases and hypercoagulability. Homocysteine is a vasculotoxic substance, and mutations in the Methyltetrahyrofolate Reductase (MTHFR) enzyme may result in an increase in serum homocysteine levels. In this report, we present a 35-year-old case with bilateral renal infarction, for which we hold the MTHFR C677T mutation and hyperhomocysteinemia responsible, because of its rarity.

引用

页码：327 / 330

页数：4

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