Serum Uric Acid Level as an Independent Mortality Marker in Patients with Acute Myocardial Infarction

Background: Hyperuricemia has been defined in patients who have congestive heart failure. Serum uric acid levels were noted in patients with acute MI and correlation with Killip's classification was studied and at the same time it was decided whether it affects mortality in such patients. Objective: To study the relationship between serum uric acid level and mortality following acute myocardial infarction. Materials and Methods: A total of 50 patients who were admitted and fulfilled the inclusion/exclusion criteria were evaluated by history, physical examination, electrocardiogram echocardiography, and serum uric acid levels. Result: Out of 50 patients, 23 were females and 27 were males. 70% patients had ST-elevated myocardial infarction (STEMI), while 30% patients were of non-STEMI. In control group, 22 were females and 28 were males. The mean age of patients was 60.06 years with age ranging from 45 to 80 years. The mean age of the control group was 58.62 years with age ranging from 47 to 80 years. Standard deviation of test group was 7.70 while of control was 7.66, so test and controls were matching for age. Conclusion: Serum uric acid levels are higher in patients of acute myocardial infarction as compared to normal healthy persons. Patients of higher Killip's class have higher uric acid levels. Patients who had myocardial infarction in past have higher serum uric acid and are in higher Killip's class.