Chemical composition and procedures are given for a cleaning method to remove nuclide contaminated particulates from the primary circuit of the deuterium moderated reactor. The procedure reduces downtime, minimizes attack on miscellaneous components and volume radioactive waste and contamination of the deuterium oxide by water as compared to other cleaning systems. The system adds a citric oxide-EDTA type cleaner directly to the coolant and removes oxide for filtration. Tests after one year showed amount of radioactivity reduced, no component failures attributed to decontamination, reduction in deuterium oxide leaks and reduced volume of insoluble crud.