NEW SYNTHETIC PROBES OF THE IRON TRANSPORT-SYSTEM OF PARACOCCUS-DENITRIFICANS

被引:9
作者
BUCKLEY, GM [1 ]
PATTENDEN, G [1 ]
WHITING, DA [1 ]
机构
[1] UNIV NOTTINGHAM,DEPT CHEM,NOTTINGHAM NG7 2RD,ENGLAND
关键词
D O I
10.1016/S0040-4020(01)85669-6
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
A range of analogues of parabactin A 4 and agrobactin A 5 have been synthesised. All these comounds were able to chelate iron, and to promote the growth of iron-starved Paracoccus denitrificans to varying degrees. A degree of flexibilty in the siderophore receptor system is thus demonstrated which may be exploitable for the transport of new siderophore - antibiotic conjugates.
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页码:11781 / 11792
页数:12
相关论文
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