Biosynthesis of Lanthanum Nanoparticles using Green Gram Seeds and their Effect on Microorganisms

The application of plant extracts in synthesis of metal nanoparticles commences to be an eco-friendly process. The study deals with synthesis of lanthanum nanoparticles using the extract of Vigna radiata (moong, green gram) beans. Green gram extract was prepared to synthesize the nanoparticles. Nanoparticles were characterized using Fourier transform Infrared Spectroscopy (FTIR) and Scanning Electron Microscopy (SEM) analysis. Antimicrobial activity of the biologically synthesized nanoparticles was tested by well diffusion technique against nine clinical pathogens. Antioxidant and anticancer studies were performed by 2,2-diphenyl1-picryl-hydrazyl-hydrate (DPPH) method and MTT[3-(4,5-Dimethylthiazol-2-yl)-2,5-Diphenyltetrazolium Bromide] assay against osteosarcoma Mg 63 cell lines respectively with the synthesized lanthanum nanoparticles to check its effectivity and future aspects of the nanoparticles. The antioxidant nature and proliferation of osteosarcoma cell lines confirms that the nanoparticles can be used in future research for anticancer drug development studies. This simple and eco-friendly approach of synthesizing nanoparticles is applicable for large scale synthesis.