IN-VITRO EVOLUTION OF NUCLEIC-ACIDS

被引：120

作者：

JOYCE, GF ^{[1
]}

机构：

[1] SCRIPPS RES INST, DEPT MOLEC BIOL, LA JOLLA, CA 92037 USA

来源：

CURRENT OPINION IN STRUCTURAL BIOLOGY | 1994年 / 4卷 / 03期

关键词：

D O I：

10.1016/S0959-440X(94)90100-7

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

An increasing number of laboratories are applying the principles of Darwinian evolution to large populations of RNA or DNA molecules to obtain compounds that bind a target ligand or catalyze a particular chemical reaction. These molecules may be useful as enzyme inhibitors or diagnostic agents.

引用

页码：331 / 336

页数：6

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