SPATIAL MEMORY DEFICITS IN AGED RATS - CONTRIBUTIONS OF THE CHOLINERGIC SYSTEM ASSESSED BY CHAT

被引：118
作者：
LUINE, V
HEARNS, M
机构：
[1] Department of Psychology, Hunter College, the City University of New York, New York
来源：
BRAIN RESEARCH | 1990年 / 523卷 / 02期
关键词：
Aging; Choline acetyltransferase; Cholinergic; Fischer; 344; Spatial memory;
D O I：
10.1016/0006-8993(90)91507-D
中图分类号：
Q189 [神经科学];
学科分类号：
071006 ;
摘要：
Activity of choline acetylase (ChAT) was measured in basal forebrain cholinergic nuclei and in projection sites of these cells in the hippocampus and cortex of young rats and of aged rats who showed impaired performance on the radial arm maze. Decreased ChAT activity was found in the vertical diagonal band nucleus, the dentate gyrus and striatum of aged rats. © 1990.
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页码：321 / 324
页数：4
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