Pauci-immune crescentic glomerulonephritis associated with use of trimethoprim-sulfamethoxazole

被引：0

作者：

Hegde, Shruti S. ^{[1
,2
]}

Bijol, Vanesa ^{[3
,4
]}

Jaber, Bertrand L. ^{[1
,2
]}

机构：

[1] St Elizabeths Med Ctr, Dept Med, Div Nephrol, 736 Cambridge St, Boston, MA 02135 USA

[2] Tufts Univ, Sch Med, Dept Med, Boston, MA 02111 USA

[3] Brigham & Womens Hosp, Dept Pathol, 75 Francis St, Boston, MA 02115 USA

[4] Harvard Med Sch, Boston, MA USA

来源：

CEN CASE REPORTS | 2016年 / 5卷 / 02期

关键词：

Trimethoprim-sulfamethoxazole; Rapidly progressive glomerulonephritis; Pauci-immune crescentic glomerulonephritis;

D O I：

10.1007/s13730-016-0222-5

中图分类号：

R5 [内科学]; R69 [泌尿科学（泌尿生殖系疾病）];

学科分类号：

1002 ; 100201 ;

摘要：

Drug-induced pauci-immune crescentic glomerulonephritis has been described with several agents, including propylthiouracil, minocycline, D-penicillamine, and hydralazine. We present the case of a 60-year-old man who presented with rapidly progressive glomerulonephritis in the setting of recent use of trimethoprim-sulfamethoxazole complicated by the development of the Stevens-Johnson syndrome, and was found to have biopsy-proven pauci-immune crescentic glomerulonephritis and undetectable anti-neutrophilic cytoplasmic antibodies. We review the existing literature on the potential association between sulfonamides and hypersensitivity polyangiitis.

引用

页码：188 / 191

页数：4

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