CHANGES IN THE FATTY-ACID COMPOSITION OF STORED ERYTHROCYTES FROM SHEEP OF DIFFERENT AGES

被引：5
|
作者：
FERNANDEZ, A [1 ]
SANCHEZYAGUE, J [1 ]
MARTINVALMASEDA, EM [1 ]
FELIPE, A [1 ]
CABEZAS, JA [1 ]
LLANILLO, M [1 ]
机构：
[1] UNIV SALAMANCA,FAC BIOL,DEPT BIOQUIM & BIOL MOLEC,E-37007 SALAMANCA,SPAIN
来源：
MECHANISMS OF AGEING AND DEVELOPMENT | 1993年 / 71卷 / 03期
关键词：
AGING; STORAGE; FATTY ACIDS; LIPID PEROXIDATION; ERYTHROCYTE MEMBRANE (SHEEP);
D O I：
10.1016/0047-6374(93)90083-4
中图分类号：
Q2 [细胞生物学];
学科分类号：
071009 ; 090102 ;
摘要：
This study examined the profile in sheep erythrocyte fatty acids from animals of different ages during storage at 4 degrees C in a nutritive medium for up to 6 days. The changes found in the fatty acyl profile were a decrease (P<0.01) in the percentage of arachidonic acid and an increase (P<0.01) in the percentage of minor fatty acids (representing < 2% in each case; 20:2, 22:0 and 22:1) with respect to fresh erythrocytes in all age groups. However, the saturated/unsaturated ratios and unsaturated index started almost constant in all cases. The changes observed occurred after 24-48 h of storage, with significant increases (P<0.01) in the fluorescence detected in the lipid extracts from stored erythrocytes during this period. The above findings suggest peroxidative damage and changes in the erythrocyte lipid membrane during storage.
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页码：189 / 198
页数：10
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