Role of Shear Wave Elastography in the Assessment of Fibrosis in Chronic Liver Disease

被引：0
作者：
Bellamkonda, Sravya [1 ]
Paruthikunnan, Samir M. [1 ]
Kadavigere, Rajagopal [1 ]
Sripathi, Smiti [1 ]
机构：
[1] Manipal Univ, Kasturba Med Coll, Dept Radiodiag & Imaging, Manipal 576104, Karnataka, India
来源：
JOURNAL OF DIAGNOSTIC MEDICAL SONOGRAPHY | 2018年 / 34卷 / 06期
关键词：
shear wave elastography; chronic liver disease; liver stiffness;
D O I：
10.1177/8756479318799340
中图分类号：
R8 [特种医学]; R445 [影像诊断学];
学科分类号：
1002 ; 100207 ; 1009 ;
摘要：
Objective: To evaluate the diagnostic performance of shear wave elastography in the estimation of fibrosis in patients with chronic liver disease by using biopsy and/or serum markers as reference standard. Materials and methods: 100 patients underwent point quantification-shear wave elastography, for whom noninvasive serum fibrosis indices like APRI, FIB-4, and King's score were calculated. The receiver-operator characteristic (ROC) curve analysis was performed. Results: The shear wave elastography measurements showed moderate agreement with APRI, FIB-4, and fair agreement with King's score. The AUROC for differentiating F0-F1, F2-F3, F2-F3, and F4 are 0.873 and 0.504 respectively using APRI as reference standard. The cutoff values derived for differentiating F0-F1 and F2-F3 was 7.07 and for differentiating F2-F3 and F4 was 11.94. Conclusion: The diagnostic performance of shear wave elastography is comparable with that of serum fibrosis indices APRI and FIB-4.
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页码：460 / 465
页数：6
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