BIOPHYSICAL STUDIES WITH SPATIALLY CORRELATED IONS .2. MULTIPLE-SCATTERING, EXPERIMENTAL FACILITY, AND DOSIMETRY

被引:13
作者
COLVETT, RD
ROHRIG, N
机构
[1] COLUMBIA UNIV COLL PHYS & SURG,DEPT RADIOL,RADIOL RES LAB,NEW YORK,NY 10032
[2] BROOKHAVEN NATL LAB,DIV SAFETY & ENVIRONM PROTECT,RADIOL RES ACCELERATOR FACIL,UPTON,NY 11973
关键词
D O I
10.2307/3575038
中图分类号
Q [生物科学];
学科分类号
07 ; 0710 ; 09 ;
摘要
Experiments examining the role of interaction distance in radiobiology have been undertaken using molecular beams which dissociate in thin Mylar cell substrates. The separate particles diverge because of multiple scattering but remain correlated. The separation between the particles follows a distribution with a characteristic separation determined by the material thickness. The relative effects of irradiation with correlated and uncorrelated particles measure an effect of interaction between the two separate tracks of the pair of particles. This paper describes the experimental facilities and dosimetry for this family of experiments. Multiple-scattering measurements are described and the shape and width of the distribution is consistent with published works. The calculations of characteristic separations between correlated pairs as they proceed through the Mylar substrate into the cell at various depths are discussed. The associated radiobiology experiments described in subsequent articles were conducted using 33 keV/μm deuterons or protons with characteristic separations between 100 and 400 nm.
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页码:192 / 209
页数:18
相关论文
共 11 条
[1]   BIOPHYSICAL STUDIES WITH SPATIALLY CORRELATED IONS .3. CELL-SURVIVAL STUDIES USING DIATOMIC DEUTERIUM [J].
BIRD, RP .
RADIATION RESEARCH, 1979, 78 (02) :210-223
[2]  
JANNI JF, 1966, AFWLTR65150 AIR FORC
[3]  
LAM YW, UNPUBLISHED
[4]   MULTIPLE SCATTERING OF CHARGED PARTICLES [J].
MARION, JB ;
ZIMMERMAN, BA .
NUCLEAR INSTRUMENTS & METHODS, 1967, 51 (01) :93-+
[5]   THEORY OF MULTIPLE SCATTERING - 2ND BORN APPROXIMATION AND CORRECTIONS TO MOLIERE WORK [J].
NIGAM, BP ;
SUNDARESAN, MK ;
WU, TY .
PHYSICAL REVIEW, 1959, 115 (03) :491-502
[7]   Multiple scattering of fast electrons and alpha-particles, and "curvature" of cloud tracks due to scattering [J].
Williams, EJ .
PHYSICAL REVIEW, 1940, 58 (04) :292-306
[8]  
Williams EJ, 1939, PROC R SOC LON SER-A, V169, P531, DOI 10.1098/rspa.1939.0015
[9]   MEASURED RADIAL DISTRIBUTIONS OF DOSE AND LET FOR ALPHA-BEAMS AND PROTON-BEAMS IN HYDROGEN AND TISSUE-EQUIVALENT GAS [J].
WINGATE, CL ;
BAUM, JW .
RADIATION RESEARCH, 1976, 65 (01) :1-19
[10]  
Ziegler J. F., 1974, Atomic Data and Nuclear Data Tables, V13, P463, DOI 10.1016/0092-640X(74)90009-6