TIGHT JUNCTIONAL STRUCTURE AND PERMEABILITY OF PORCINE JEJUNUM AFTER ENTEROTOXIC ESCHERICHIA-COLI INFECTION

被引：9

作者：

EGBERTS, HJA ^{[1
]}

DEGROOT, ECBM ^{[1
]}

VANDIJK, JE ^{[1
]}

VELLENGA, L ^{[1
]}

MOUWEN, JMVM ^{[1
]}

机构：

[1] UNIV UTRECHT,LARGE ANIM MED CLIN,UTRECHT,NETHERLANDS

来源：

RESEARCH IN VETERINARY SCIENCE | 1993年 / 55卷 / 01期

关键词：

D O I：

10.1016/0034-5288(93)90026-C

中图分类号：

S85 [动物医学（兽医学）];

学科分类号：

0906 ;

摘要：

Tight junctional structure and macromolecular permeability were tested in four three-week-old piglets, experimentally infected with the enterotoxigenic Escherichia Coli (ETEC) strain 0149 K91 K88. Histologically, only minor microscopic evidence of inflammation and little or no architectural changes in the jejunal mucosa were observed. A significant decrease in tight junctional strand numbers occurred, without a concomitant decrease in tight junctional depth. The permeability of the porcine jejunal epithelium to horseradish peroxidase did not change after the ETEC infection.

引用

页码：10 / 14

页数：5

共 21 条

[1] THE ROLE OF EPITHELIAL-CELLS IN GUT-ASSOCIATED IMMUNE REACTIVITY [J].