ENDEMIC VISCERAL LEISHMANIASIS IN A DOG FROM TEXAS

被引:26
作者
SELLON, RK [1 ]
MENARD, MM [1 ]
MEUTEN, DJ [1 ]
LENGERICH, EJ [1 ]
STEURER, FJ [1 ]
BREITSCHWERDT, EB [1 ]
机构
[1] N CAROLINA STATE UNIV,DEPT COMPAN ANIM & SPECIAL SPECIES MED,4700 HILLSBOROUGH ST,RALEIGH,NC 27695
关键词
D O I
10.1111/j.1939-1676.1993.tb03163.x
中图分类号
S85 [动物医学(兽医学)];
学科分类号
0906 ;
摘要
Visceral leishmaniasis was diagnosed by cytology and positive indirect immunofluorescent antibody titers to Leishmania donovani in a 7‐month‐old female Basenji dog from Texas. Clinical and laboratory findings included weight loss, hematochezia, hyperglobulinemia, hypoalbuminemia, anemia, and neutrophilic leukocytosis. Evidence of response to treatment with diminazene aceturate and ketoconazole included improvement in the abnormal clinical, hematologic, and biochemical findings, decreased serum globulin concentration and antibody titer to Leishmania donovani, and absence of organisms in examined tissues. Several foci of endemic leishmaniasis have been reported in the United States. Because of its zoonotic potential and the lack of approved treatments for dogs with leishmaniasis in the United States, the development of effective treatment strategies is needed. © 1993 American College of Veterinary Internal Medicine
引用
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页码:16 / 19
页数:4
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