EFFECT OF PENTOBARBITAL ON THE SPONTANEOUS EFFLUX OF GAMMA-AMINO ACIDS FROM RABBIT RETINA

被引：7

作者：

BAUER, B ^{[1
]}

机构：

[1] UNIV LUND,DEPT HISTOL,S-22101 LUND,SWEDEN

来源：

BRAIN RESEARCH | 1979年 / 163卷 / 02期

关键词：

D O I：

10.1016/0006-8993(79)90358-5

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

The effect of pentobarbitone on the spontaneous release of radioactivity from rabbit retinas preloaded with [3H]GABA, [3H]DABA, [3H]β-alanine and [3H]glycine was studied. In high concentration of pentobarbitone (10-3 M) the rate of spontaneous efflux of neuronal [3H]GABA, [3H]DABA and [3H]β-alanine was reduced but not that of [3H]glycine. Glial release of [3H]GABA was much less influenced. At lower concentrations (10-4-10-5 M) there was an initial increase in the release of [3H]GABA, [3H]DABA and [3H]β-alanine followed by a decrease, indicating several components in the release systems for the amino acids. © 1979.

引用

页码：307 / 317

页数：11

共 24 条

[1]

Ames A., 1965, BIOCHEMISTRY RETINA, P22

[2] LIGHT EVOKED RELEASE OF RADIOACTIVITY FROM RABBIT RETINAS PRELOADED WITH GABA-H-3 [J].