MONOCLONAL IGM REACTIVE WITH SEVERAL GANGLIOSIDES IN A CHRONIC RELAPSING POLYNEUROPATHY

被引：23
作者：
BRINDEL, I
PREUDHOMME, JL
VALLAT, JM
VINCENT, D
VASQUEZ, JL
JAUBERTEAU, MO
机构：
[1] LIMOGES UNIV HOSP,IMMUNOL LABS,F-87042 LIMOGES,FRANCE
[2] UNIV POITIERS HOSP,CNRS,URA 1172,POITIERS,FRANCE
[3] LIMOGES UNIV HOSP,DEPT NEUROL,F-87042 LIMOGES,FRANCE
来源：
NEUROSCIENCE LETTERS | 1994年 / 181卷 / 1-2期
关键词：
CHRONIC RELAPSING POLYNEUROPATHY; MONOCLONAL IGM; GANGLIOSIDES; DISIALOSYL-LACTOSYL RESIDUE;
D O I：
10.1016/0304-3940(94)90570-3
中图分类号：
Q189 [神经科学];
学科分类号：
071006 ;
摘要：
A possibly pathogenic serum monoclonal IgM lambda from a patient with chronic relapsing polyneuropathy was shown to react with the disialosyl-lactosyl residue (NeuAc alpha 2-8NeuAc alpha 2-3)-Gal beta 1-Glc expressed by GD1b, GT1b, GQ1b, GD2 and GD3. A part of this epitope in terminal position in GM3, GD1a and LM1 was also recognized by the IgM lambda.
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页码：103 / 106
页数：4
相关论文
共 12 条
[1]   MYELIN-ASSOCIATED GLYCOPROTEIN IS THE ANTIGEN FOR A MONOCLONAL IGM IN POLYNEUROPATHY [J].
BRAUN, PE ;
FRAIL, DE ;
LATOV, N .
JOURNAL OF NEUROCHEMISTRY, 1982, 39 (05) :1261-1265
[2]  
BRIAULT S, 1988, CLIN EXP IMMUNOL, V74, P182
[3]  
CHOU KH, 1985, J NEUROCHEM, V44, P1998
[4]  
COULONMORELEC MJ, 1972, ANN I PASTEUR PARIS, V123, P619
[5]   SENSORY NEUROPATHY ASSOCIATED WITH MONOCLONAL IMMUNOGLOBULIN-M TO GD1B GANGLIOSIDE [J].
DAUNE, GC ;
FARRER, RG ;
DALAKAS, MC ;
QUARLES, RH .
ANNALS OF NEUROLOGY, 1992, 31 (06) :683-685
[6]  
DUBOIS C, 1986, J BIOL CHEM, V261, P3826
[7]   A NEW METHOD FOR PURIFICATION OF ANTI-GLYCOSPHINGOLIPID ANTIBODY - AVIAN ANTI-HEMATOSIDE (NEUGC) ANTIBODY [J].
HIRABAYASHI, Y ;
SUZUKI, T ;
SUZUKI, Y ;
TAKI, T ;
MATSUMOTO, M ;
HIGASHI, H ;
KATO, S .
JOURNAL OF BIOCHEMISTRY, 1983, 94 (01) :327-330
[8]   MONOCLONAL IGM IN A PATIENT WITH PARAPROTEINEMIC POLYNEUROPATHY BINDS TO GANGLIOSIDES CONTAINING DISIALOSYL GROUPS [J].
ILYAS, AA ;
QUARLES, RH ;
DALAKAS, MC ;
FISHMAN, PH ;
BRADY, RO .
ANNALS OF NEUROLOGY, 1985, 18 (06) :655-659
[9]   AFFINITY IMMUNOBLOTTING DETECTION OF SERUM MONOCLONAL IMMUNOGLOBULINS REACTIVE WITH GLYCOSPHINGOLIPIDS [J].
JAUBERTEAU, MO ;
COOK, JM ;
DROUET, M ;
PREUDHOMME, JL .
JOURNAL OF IMMUNOLOGICAL METHODS, 1990, 134 (01) :107-112
[10]  
JAUBERTEAU MO, 1990, CLIN EXP IMMUNOL, V80, P186
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