CARBOCYCLIC ANALOGS OF 3',4'-DIDEHYDRO-2'-DEOXYRIBOFURANOSYL-2,4(1H,3H)-PYRIMIDINEDIONES

被引：7
作者：
ODELL, CA [1 ]
SHEALY, YF [1 ]
机构：
[1] SO RES INST,ORGAN CHEM RES DEPT,BIRMINGHAM,AL 35255
来源：
NUCLEOSIDES & NUCLEOTIDES | 1994年 / 13卷 / 09期
基金：
美国国家卫生研究院;
关键词：
D O I：
10.1080/15257779408010673
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
A new method for obtaining carbocyclic analogues of 3',4'-didehydro-2,4(1H,3H)-pyrimidinedione nucleosides in good yields consists of the reaction of the carbocyclic 2,3'-anhydronucleosides with lithium chloride in dimethylformamide. Small amounts of the carbocyclic 2',3'-didehydro isomers are formed simultaneously. The carbocyclic 2,3'-anhydronucleosides were obtained by treating carbocyclic 5'-trityl derivatives with DAST.
引用
收藏
页码：1929 / 1937
页数：9
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