THE SIZE OF HYDROXYL-GROUPS IN SOLUTION AND THE CHANGES IN SIZE ASSOCIATED WITH THE IONIZATION OF PHENOLIC, CARBOXYLIC AND AMINO-GROUPS IN PHENOLIC QUATERNARY AMMONIUM-SALTS, NICOTINE AND SOME AMINO-ACIDS - POSSIBLE IMPLICATIONS FOR DRUG-WATER AND DRUG-RECEPTOR INTERACTIONS

被引：8

作者：

BARLOW, RB

机构：

来源：

BRITISH JOURNAL OF PHARMACOLOGY | 1980年 / 71卷 / 01期

关键词：

D O I：

10.1111/j.1476-5381.1980.tb10904.x

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

引用

收藏

页码：17 / 30

页数：14

相关论文

共 30 条

[1] RELATIONSHIPS BETWEEN CHEMICAL-STRUCTURE AND AFFINITY FOR POSTGANGLIONIC ACETYLCHOLINE RECEPTORS OF GUINEA-PIG ILEUM [J].

ABRAMSON, FB ;

BARLOW, RB ;

FRANKS, FM ;

PEARSON, JDM .

BRITISH JOURNAL OF PHARMACOLOGY, 1974, 51 (01) :81-93

[2] TEMPERATURE COEFFICIENTS OF AFFINITY AND ENTROPIES OF ADSORPTION FOR ENANTIOMERIC PAIRS OF COMPOUNDS ACTING AT MUSCARINIC RECEPTORS IN THE GUINEA-PIG ILEUM [J].

BARLOW, RB ;

BURSTON, KN .

BRITISH JOURNAL OF PHARMACOLOGY, 1979, 66 (04) :581-585

[3] EFFECTS OF A HYDROXYL GROUP ON SOME CHEMICAL AND BIOLOGICAL PROPERTIES OF N-PENTYL AMMONIUM-SALTS [J].

BARLOW, RB .

JOURNAL OF PHARMACY AND PHARMACOLOGY, 1978, 30 (11) :703-710

[4] AFFINITY AND ACTIVITY OF COMPOUNDS RELATED TO NICOTINE ON RECTUS ABDOMINIS MUSCLE OF FROG (RANA PIPIENS) [J].

BARLOW, RB ;

THOMPSON, GM ;

SCOTT, NC .

BRITISH JOURNAL OF PHARMACOLOGY, 1969, 37 (03) :555-&

[5] THE IONIZATION OF 5-HYDROXYTRYPTAMINE AND RELATED-COMPOUNDS AND AN APPRAISAL OF METHODS FOR THE ESTIMATION OF ZWITTERION CONSTANTS [J].

BARLOW, RB ;

BURSTON, KN .

BRITISH JOURNAL OF PHARMACOLOGY, 1980, 69 (04) :587-595

[6] TEMPERATURE COEFFICIENTS OF AFFINITY CONSTANTS FOR THE BINDING OF ANTAGONISTS TO MUSCARINIC RECEPTORS IN THE RAT CEREBRAL-CORTEX [J].

BARLOW, RB ;

BIRDSALL, NJM ;

HULME, EC .

BRITISH JOURNAL OF PHARMACOLOGY, 1979, 66 (04) :587-590

[7] PHYSICOCHEMICAL PROPERTIES AND BIOLOGICAL-ACTIVITY - THERMODYNAMIC PROPERTIES OF COMPOUNDS RELATED TO ACETYLCHOLINE ASSESSED FROM DEPRESSION OF FREEZING-POINT AND ENTHALPIES OF DILUTION [J].

BARLOW, RB .

BRITISH JOURNAL OF PHARMACOLOGY, 1974, 51 (03) :413-426

[8] COMPARISON OF AFFINITY CONSTANTS FOR MUSCARINE-SENSITIVE ACETYLCHOLINE RECEPTORS IN GUINEA-PIG ATRIAL PACEMAKER CELLS AT 29 DEGREESC AND IN ILEUM AT 29 DEGREESC AND 37 DEGREESC [J].

BARLOW, RB ;

BERRY, KJ ;

GLENTON, PAM ;

NIKOLAOU, NM ;

SOH, KS .

BRITISH JOURNAL OF PHARMACOLOGY, 1976, 58 (04) :613-620

[9] COMPARISON OF PHENYLALKYL-TRIMETHYLAMMONIUM AND PHENOXYALKYL-TRIMETHYLAMMONIUM AND TRIETHYLAMMONIUM SALTS - THEIR APPARENT MOLAL VOLUMES AT INFINITE DILUTION AND EFFECTS ON FROG RECTUS AND GUINEA-PIG ILEUM PREPARATIONS [J].

BARLOW, RB ;

FRANKS, FM .

BRITISH JOURNAL OF PHARMACOLOGY, 1973, 49 (03) :480-489

[10] THE SIZE OF THE HYDROXYL GROUP AND ITS CONTRIBUTION TO THE AFFINITY OF ATROPINE FOR MUSCARINE-SENSITIVE ACETYLCHOLINE-RECEPTORS [J].

BARLOW, RB ;

RAMTOOLA, S .

BRITISH JOURNAL OF PHARMACOLOGY, 1980, 71 (01) :31-34