OCCURRENCE OF 5-METHOXYTRYPTAMINE IN BRAIN

被引：12

作者：

BOSIN, TR

JONSSON, G

BECK, O

机构：

[1] KAROLINSKA INST,MRC,DEPT TOXICOL,S-10401 STOCKHOLM 60,SWEDEN

[2] KAROLINSKA INST,DEPT HISTOL,S-10401 STOCKHOLM 60,SWEDEN

来源：

BRAIN RESEARCH | 1979年 / 173卷 / 01期

基金：

美国国家卫生研究院;

关键词：

D O I：

10.1016/0006-8993(79)91097-7

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

A quantitative gas chromatography-mass spectrometry method has been used to determine 5-methoxytryptamine (5-MT) in the CNS and pineal gland of various species. The mean ± S.D. levels of 5-MT in sheep, pig and cow pineal glands was 545 ± 180, 228 ± 119 and 117 ± 48 pmol/g, respectively. The postmortem levels of 5-MT in the pig pineal gland was stable for 2 h after death but decreased by more than 90% 24 h after death. In the CNS, 5-MT was found only in the sheep hypothalamus (28 ± 4 pmol/g). Analysis of the rat pineal gland and CNS failed to detect any 5-MT at the limit of sensitivity of the method which is at variance with previously reported results. © 1979.

引用

页码：79 / 88

页数：10

共 26 条

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[2]

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