TOTAL ANTIOXIDANT ACTIVITY OF LOW-DENSITY LIPOPROTEINS AND THE RELATIONSHIP WITH ALPHA-TOCOPHEROL STATUS

被引：20
作者：
MILLER, NJ
PAGANGA, G
WISEMAN, S
VANNIELEN, W
TIJBURG, L
CHOWIENCZYK, P
RICEEVANS, CA
机构：
[1] UNITED MED & DENT SCH,GUYS HOSP,FREE RAD RES GRP,LONDON SE1 9RT,ENGLAND
[2] UNITED MED & DENT SCH,GUYS HOSP,DEPT CLIN PHARMACOL,LONDON SE1 9RT,ENGLAND
[3] UNILEVER RES LABS VLAARDINGEN,3130 AC VLAARDINGEN,NETHERLANDS
来源：
FEBS LETTERS | 1995年 / 365卷 / 2-3期
关键词：
ANTIOXIDANT ACTIVITY; LOW DENSITY LIPOPROTEIN; ABTS(.+); VITAMIN-E;
D O I：
10.1016/0014-5793(95)00448-I
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
A rapid method is described for measuring the antioxidant activity of low density lipoproteins. Studies were undertaken on individuals attending a hyperlipidaemia clinic, an unsupplemented group and a group after supplementation with 300 mg dl-alpha-tocopherol acetate for nine weeks, The results show a positive correlation between the antioxidant activity and alpha-tocopherol content of LDL in the supplemented group.
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收藏
页码：164 / 166
页数：3
相关论文
共 24 条
  • [1] BERGMEYER HU, 1983, METHODS ENZYM ANAL, V3, P277
  • [2] BIERI JG, 1977, AM J CLIN NUTR, V40, P747
  • [3] CHUNG BH, 1980, J LIPID RES, V21, P284
  • [4] ENDOGENOUS ANTIOXIDANTS AND LIPOPROTEIN OXIDATION
    ESTERBAUER, H
    DIEBERROTHENEDER, M
    WAEG, G
    PUHL, H
    TATZBER, F
    [J]. BIOCHEMICAL SOCIETY TRANSACTIONS, 1990, 18 (06) : 1059 - 1061
  • [5] THE ROLE OF LIPID-PEROXIDATION AND ANTIOXIDANTS IN OXIDATIVE MODIFICATION OF LDL
    ESTERBAUER, H
    GEBICKI, J
    PUHL, H
    JURGENS, G
    [J]. FREE RADICAL BIOLOGY AND MEDICINE, 1992, 13 (04) : 341 - 390
  • [6] GEY KF, 1994, IN PRESS FREE RADICA, P181
  • [7] A FLUORESCENCE-BASED METHOD FOR MEASURING TOTAL PLASMA ANTIOXIDANT CAPABILITY
    GHISELLI, A
    SERAFINI, M
    MAIANI, G
    AZZINI, E
    FERROLUZZI, A
    [J]. FREE RADICAL BIOLOGY AND MEDICINE, 1995, 18 (01) : 29 - 36
  • [8] HALLIWELL B, 1995, IN PRESS FREE RADICA
  • [9] KAGAN VE, 1992, J LIPID RES, V33, P385
  • [10] MODIFICATION OF LOWRY PROCEDURE TO SIMPLIFY PROTEIN DETERMINATION IN MEMBRANE AND LIPOPROTEIN SAMPLES
    MARKWELL, MAK
    HAAS, SM
    BIEBER, LL
    TOLBERT, NE
    [J]. ANALYTICAL BIOCHEMISTRY, 1978, 87 (01) : 206 - 210
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