EXPERIMENTAL TRACHEAL REVASCULARIZATION WITH OMENTUM

被引:4
作者
LOPEZRIVERO, L
QUEVEDO, S
FREIXINET, J
DECASTRO, FR
LIMINANA, M
SALVATIERRA, A
LOPEZPUJOL, J
机构
[1] Department of Thoracic Surgery, Las Palmas
[2] Department of Biostatistics, University of Las Palmas, Las Palmas
[3] Department of Thoracic Surgery, Hospital Reina Sofia, Cordoba
关键词
TRACHEA; REVASCULARIZATION; OMENTUM; ALLOTRANSPLANTATION;
D O I
10.1016/1010-7940(93)90053-E
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
We assessed omental revascularization of heterotopic tracheal implants in rats, and investigated the influence of factors that can enhance revascularization. The trachea of the donor animal was excised in two parts, and each tracheal allograft was implanted in the omentum of two recipients. The influence of mechanical factors was evaluated by applying traction at both ends of the graft with and without drainage of the tracheal lumen, and the influence of pharmacologic factors by giving cefonicid, hydrocortisone, cefonicid plus hydrocortisone, or cyclosporine and azathioprine during the postoperative period. Revascularization of the graft from the omentum with presevation of the tracheal structure was established. Graft viability showed significant differences between the tracheal implants to which no traction had been applied and those with traction at both ends. Tracheal allografts from animals receiving immunosuppressants were completely viable and no significant differences were found between the controls and animals in this group.
引用
收藏
页码:540 / 542
页数:3
相关论文
共 12 条
[1]  
Balderman S.C., Weinblatt G., Tracheal autograft revascu- larization, J Thorac Cardiovasc Surg, 94, pp. 434-441, (1987)
[2]  
Dubois P., Choiniere C.C., Cooper J.D., Bronchial omen- topexy in canine lung allo transplantation, Ann Thorac Surg, 38, pp. 211-213, (1984)
[3]  
Greenberg B.M., Low D., Rosat E., The use of omental graft in operations performed upon the colon and rectum, Surg Gynecol Obstet, 161, pp. 487-488, (1985)
[4]  
Grill0 H.E., Primary reconstruction of airway after resection of subglottic laryngeal and upper tracheal stenosis, Ann Thorac Surg, 44, pp. 680-681, (1982)
[5]  
Grill0 H.E., Dignan E.F., Miura Y., Extensive resection and reconstruction of mediastinal trachea with prosthesis or graft: An anatomical study in man, J Thorac Cardiovasc Surg, 48, (1964)
[6]  
Michelson E., Solomon R., Mavi L., Ramirez J., Experi- ments in tracheal reconstruction, J Thorac Surg, 41, pp. 748-759, (1981)
[7]  
Morgan E., Lima 0 G.M., Ferdman A., Luk S.K., Coope J.D., Successful revascularization of totally ischemic bronchial auto grafts with mental pedicle flaps in dogs, J Thorat Cardiovasc Surg, 84, pp. 204-210, (1982)
[8]  
Moriyama S., Shimizu N., Teramoto S., Experimental tracheal allo transplantation using omentopexy, Transplant Proc, 21, pp. 2596-2600, (1989)
[9]  
Morrison R., Remarks on some functions of the omen turn, BMJ, 1, pp. 76-79, (1906)
[10]  
Neville N.E., Bolanowski P., Kotia G.G., Clinical experience with the silicone tracheal prosthesis, J Thorac Cardiovasc Surg, 99, pp. 604-613, (1990)