PLANAR MICRO SENSORS FOR IN-VIVO MYOCARDIAL PH MEASUREMENTS

被引：26
作者：
COSOFRET, VV
LINDNER, E
JOHNSON, TA
NEUMAN, MR
机构：
[1] UNIV N CAROLINA,SCH MED,DIV CARDIOL,CHAPEL HILL,NC 27599
[2] CASE WESTERN RESERVE UNIV,METRO HLTH MED CTR,DEPT OBSTET GYNECOL,CLEVELAND,OH 44109
来源：
TALANTA | 1994年 / 41卷 / 06期
关键词：
D O I：
10.1016/0039-9140(94)E0106-2
中图分类号：
O65 [分析化学];
学科分类号：
070302 ; 081704 ;
摘要：
Potentiometric responses of microelectronically fabricated planar pH sensors based on both TDDA or ETH 5294 proton neutral carriers, in aminated PVC matrix, were evaluated with respect to main analytical parameters (linear ranges, slopes, reproducibility of potential measurements, potential drift and membrane resistance). In order to increase the electrode life time, increased amounts of membrane material were applied on the Ag/AgCl-poly-HEMA active spots of the polyimide substrate. The electrodes were implanted into an in situ porcine beating heart preparation at a midmyocardial depth in order to monitor H+ concentration changes during the course of coronary artery occlusion.
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页码：931 / 938
页数：8
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