INFLUENCE OF UV IRRADIATION ON THE COMPOSITION OF HUMAN STRATUM-CORNEUM LIPIDS

被引：58

作者：

WEFERS, H ^{[1
]}

MELNIK, BC ^{[1
]}

FLUR, M ^{[1
]}

BLUHM, C ^{[1
]}

LEHMANN, P ^{[1
]}

PLEWIG, G ^{[1
]}

机构：

[1] UNIV DUSSELDORF,DEPT DERMATOL,LIPID RES LAB,MOORENSTR 5,W-4000 DUSSELDORF 1,GERMANY

来源：

JOURNAL OF INVESTIGATIVE DERMATOLOGY | 1991年 / 96卷 / 06期

关键词：

D O I：

10.1111/1523-1747.ep12476124

中图分类号：

R75 [皮肤病学与性病学];

学科分类号：

100206 ;

摘要：

Irradiation with suberthemal doses of either UV-A or UV-B yielded an increase in the amount of stratum corneum lipids extracted from the lumbar skin area of 20 volunteers. These lipids were quantified after separation by high-performance thin-layer chromatography. Ten subfractions in the ceramide region were separated; two of them (fractions 7a and 7b) were only detectable after UV-A or UV-B irradiation. Improvement of barrier function after UV irradiation of human skin with suberythemal doses may be related to an increase in the stratum corneum ceramides.

引用

页码：959 / 962

页数：4

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