INFLUENCE OF UV IRRADIATION ON THE COMPOSITION OF HUMAN STRATUM-CORNEUM LIPIDS

被引：58
|
作者：
WEFERS, H [1 ]
MELNIK, BC [1 ]
FLUR, M [1 ]
BLUHM, C [1 ]
LEHMANN, P [1 ]
PLEWIG, G [1 ]
机构：
[1] UNIV DUSSELDORF,DEPT DERMATOL,LIPID RES LAB,MOORENSTR 5,W-4000 DUSSELDORF 1,GERMANY
来源：
JOURNAL OF INVESTIGATIVE DERMATOLOGY | 1991年 / 96卷 / 06期
关键词：
D O I：
10.1111/1523-1747.ep12476124
中图分类号：
R75 [皮肤病学与性病学];
学科分类号：
100206 ;
摘要：
Irradiation with suberthemal doses of either UV-A or UV-B yielded an increase in the amount of stratum corneum lipids extracted from the lumbar skin area of 20 volunteers. These lipids were quantified after separation by high-performance thin-layer chromatography. Ten subfractions in the ceramide region were separated; two of them (fractions 7a and 7b) were only detectable after UV-A or UV-B irradiation. Improvement of barrier function after UV irradiation of human skin with suberythemal doses may be related to an increase in the stratum corneum ceramides.
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收藏
页码：959 / 962
页数：4
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